Variation in pentose phosphate pathway-associated metabolism dictates cytotoxicity outcomes determined by tetrazolium reduction assays

Tetrazolium reduction and resazurin assays are the mainstay of routine in vitro toxicity batteries. However, potentially erroneous characterization of cytotoxicity and cell proliferation can arise if verification of baseline interaction of test article with method employed is neglected. The current...

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Detalles Bibliográficos
Autores principales: Coyle, Jayme P., Johnson, Caroline, Jensen, Jake, Farcas, Mariana, Derk, Raymond, Stueckle, Todd A., Kornberg, Tiffany G., Rojanasakul, Yon, Rojanasakul, Liying W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203251/
https://www.ncbi.nlm.nih.gov/pubmed/37217524
http://dx.doi.org/10.1038/s41598-023-35310-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203251/
https://www.ncbi.nlm.nih.gov/pubmed/37217524
http://dx.doi.org/10.1038/s41598-023-35310-5

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