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Variation in pentose phosphate pathway-associated metabolism dictates cytotoxicity outcomes determined by tetrazolium reduction assays
Tetrazolium reduction and resazurin assays are the mainstay of routine in vitro toxicity batteries. However, potentially erroneous characterization of cytotoxicity and cell proliferation can arise if verification of baseline interaction of test article with method employed is neglected. The current...
Autores principales: | Coyle, Jayme P., Johnson, Caroline, Jensen, Jake, Farcas, Mariana, Derk, Raymond, Stueckle, Todd A., Kornberg, Tiffany G., Rojanasakul, Yon, Rojanasakul, Liying W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203251/ https://www.ncbi.nlm.nih.gov/pubmed/37217524 http://dx.doi.org/10.1038/s41598-023-35310-5 |
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