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Distinct beta frequencies reflect categorical decisions

Based on prior findings of content-specific beta synchronization in working memory and decision making, we hypothesized that beta oscillations support the (re-)activation of cortical representations by mediating neural ensemble formation. We found that beta activity in monkey dorsolateral prefrontal...

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Autores principales: Rassi, Elie, Zhang, Yi, Mendoza, Germán, Méndez, Juan Carlos, Merchant, Hugo, Haegens, Saskia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203257/
https://www.ncbi.nlm.nih.gov/pubmed/37217510
http://dx.doi.org/10.1038/s41467-023-38675-3
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author Rassi, Elie
Zhang, Yi
Mendoza, Germán
Méndez, Juan Carlos
Merchant, Hugo
Haegens, Saskia
author_facet Rassi, Elie
Zhang, Yi
Mendoza, Germán
Méndez, Juan Carlos
Merchant, Hugo
Haegens, Saskia
author_sort Rassi, Elie
collection PubMed
description Based on prior findings of content-specific beta synchronization in working memory and decision making, we hypothesized that beta oscillations support the (re-)activation of cortical representations by mediating neural ensemble formation. We found that beta activity in monkey dorsolateral prefrontal cortex (dlPFC) and pre-supplementary motor area (preSMA) reflects the content of a stimulus in relation to the task context, regardless of its objective properties. In duration- and distance-categorization tasks, we changed the boundary between categories from one block of trials to the next. We found that two distinct beta-band frequencies were consistently associated with the two relative categories, with activity in these bands predicting the animals’ responses. We characterized beta at these frequencies as transient bursts, and showed that dlPFC and preSMA are connected via these distinct frequency channels. These results support the role of beta in forming neural ensembles, and further show that such ensembles synchronize at different beta frequencies.
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spelling pubmed-102032572023-05-24 Distinct beta frequencies reflect categorical decisions Rassi, Elie Zhang, Yi Mendoza, Germán Méndez, Juan Carlos Merchant, Hugo Haegens, Saskia Nat Commun Article Based on prior findings of content-specific beta synchronization in working memory and decision making, we hypothesized that beta oscillations support the (re-)activation of cortical representations by mediating neural ensemble formation. We found that beta activity in monkey dorsolateral prefrontal cortex (dlPFC) and pre-supplementary motor area (preSMA) reflects the content of a stimulus in relation to the task context, regardless of its objective properties. In duration- and distance-categorization tasks, we changed the boundary between categories from one block of trials to the next. We found that two distinct beta-band frequencies were consistently associated with the two relative categories, with activity in these bands predicting the animals’ responses. We characterized beta at these frequencies as transient bursts, and showed that dlPFC and preSMA are connected via these distinct frequency channels. These results support the role of beta in forming neural ensembles, and further show that such ensembles synchronize at different beta frequencies. Nature Publishing Group UK 2023-05-22 /pmc/articles/PMC10203257/ /pubmed/37217510 http://dx.doi.org/10.1038/s41467-023-38675-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Rassi, Elie
Zhang, Yi
Mendoza, Germán
Méndez, Juan Carlos
Merchant, Hugo
Haegens, Saskia
Distinct beta frequencies reflect categorical decisions
title Distinct beta frequencies reflect categorical decisions
title_full Distinct beta frequencies reflect categorical decisions
title_fullStr Distinct beta frequencies reflect categorical decisions
title_full_unstemmed Distinct beta frequencies reflect categorical decisions
title_short Distinct beta frequencies reflect categorical decisions
title_sort distinct beta frequencies reflect categorical decisions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203257/
https://www.ncbi.nlm.nih.gov/pubmed/37217510
http://dx.doi.org/10.1038/s41467-023-38675-3
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