Asymmetric α-allylic allenylation of β-ketocarbonyls and aldehydes by synergistic Pd/chiral primary amine catalysis

We herein describe an asymmetric α-allylic allenylation of β-ketocarbonyls and aldehydes with 1,3-enynes. A synergistic chiral primary amine/Pd catalyst was identified to facilitate the utilization of 1,3-enynes as atom-economic and achiral allene precursors. The synergistic catalysis enables the co...

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Detalles Bibliográficos
Autores principales: You, Chang, Shi, Mingying, Mi, Xueling, Luo, Sanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203310/
https://www.ncbi.nlm.nih.gov/pubmed/37217465
http://dx.doi.org/10.1038/s41467-023-38488-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203310/
https://www.ncbi.nlm.nih.gov/pubmed/37217465
http://dx.doi.org/10.1038/s41467-023-38488-4

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