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Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants
N(6)-Methyladenosine (m(6)A) is the most abundant internal chemical modification in eukaryotic mRNA and plays important roles in gene expression regulation, including transcriptional and post-transcriptional regulation. m(6)A is a reversible modification that is installed, removed, and recognized by...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203383/ https://www.ncbi.nlm.nih.gov/pubmed/36627844 http://dx.doi.org/10.1016/j.xplc.2023.100546 |
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author | Tang, Jun Chen, Shuyan Jia, Guifang |
author_facet | Tang, Jun Chen, Shuyan Jia, Guifang |
author_sort | Tang, Jun |
collection | PubMed |
description | N(6)-Methyladenosine (m(6)A) is the most abundant internal chemical modification in eukaryotic mRNA and plays important roles in gene expression regulation, including transcriptional and post-transcriptional regulation. m(6)A is a reversible modification that is installed, removed, and recognized by methyltransferases (writers), demethylases (erasers), and m(6)A-binding proteins (readers), respectively. Recently, the breadth of research on m(6)A in plants has expanded, and the vital roles of m(6)A in plant development, biotic and abiotic stress responses, and crop trait improvement have been investigated. In this review, we discuss recent developments in research on m(6)A and highlight the detection methods, distribution, regulatory proteins, and molecular and biological functions of m(6)A in plants. We also offer some perspectives on future investigations, providing direction for subsequent research on m(6)A in plants. |
format | Online Article Text |
id | pubmed-10203383 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-102033832023-05-24 Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants Tang, Jun Chen, Shuyan Jia, Guifang Plant Commun Review Article N(6)-Methyladenosine (m(6)A) is the most abundant internal chemical modification in eukaryotic mRNA and plays important roles in gene expression regulation, including transcriptional and post-transcriptional regulation. m(6)A is a reversible modification that is installed, removed, and recognized by methyltransferases (writers), demethylases (erasers), and m(6)A-binding proteins (readers), respectively. Recently, the breadth of research on m(6)A in plants has expanded, and the vital roles of m(6)A in plant development, biotic and abiotic stress responses, and crop trait improvement have been investigated. In this review, we discuss recent developments in research on m(6)A and highlight the detection methods, distribution, regulatory proteins, and molecular and biological functions of m(6)A in plants. We also offer some perspectives on future investigations, providing direction for subsequent research on m(6)A in plants. Elsevier 2023-01-10 /pmc/articles/PMC10203383/ /pubmed/36627844 http://dx.doi.org/10.1016/j.xplc.2023.100546 Text en © 2023. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Tang, Jun Chen, Shuyan Jia, Guifang Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants |
title | Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants |
title_full | Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants |
title_fullStr | Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants |
title_full_unstemmed | Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants |
title_short | Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants |
title_sort | detection, regulation, and functions of rna n(6)-methyladenosine modification in plants |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203383/ https://www.ncbi.nlm.nih.gov/pubmed/36627844 http://dx.doi.org/10.1016/j.xplc.2023.100546 |
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