Cargando…

Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants

N(6)-Methyladenosine (m(6)A) is the most abundant internal chemical modification in eukaryotic mRNA and plays important roles in gene expression regulation, including transcriptional and post-transcriptional regulation. m(6)A is a reversible modification that is installed, removed, and recognized by...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Jun, Chen, Shuyan, Jia, Guifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203383/
https://www.ncbi.nlm.nih.gov/pubmed/36627844
http://dx.doi.org/10.1016/j.xplc.2023.100546
_version_ 1785045618336464896
author Tang, Jun
Chen, Shuyan
Jia, Guifang
author_facet Tang, Jun
Chen, Shuyan
Jia, Guifang
author_sort Tang, Jun
collection PubMed
description N(6)-Methyladenosine (m(6)A) is the most abundant internal chemical modification in eukaryotic mRNA and plays important roles in gene expression regulation, including transcriptional and post-transcriptional regulation. m(6)A is a reversible modification that is installed, removed, and recognized by methyltransferases (writers), demethylases (erasers), and m(6)A-binding proteins (readers), respectively. Recently, the breadth of research on m(6)A in plants has expanded, and the vital roles of m(6)A in plant development, biotic and abiotic stress responses, and crop trait improvement have been investigated. In this review, we discuss recent developments in research on m(6)A and highlight the detection methods, distribution, regulatory proteins, and molecular and biological functions of m(6)A in plants. We also offer some perspectives on future investigations, providing direction for subsequent research on m(6)A in plants.
format Online
Article
Text
id pubmed-10203383
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-102033832023-05-24 Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants Tang, Jun Chen, Shuyan Jia, Guifang Plant Commun Review Article N(6)-Methyladenosine (m(6)A) is the most abundant internal chemical modification in eukaryotic mRNA and plays important roles in gene expression regulation, including transcriptional and post-transcriptional regulation. m(6)A is a reversible modification that is installed, removed, and recognized by methyltransferases (writers), demethylases (erasers), and m(6)A-binding proteins (readers), respectively. Recently, the breadth of research on m(6)A in plants has expanded, and the vital roles of m(6)A in plant development, biotic and abiotic stress responses, and crop trait improvement have been investigated. In this review, we discuss recent developments in research on m(6)A and highlight the detection methods, distribution, regulatory proteins, and molecular and biological functions of m(6)A in plants. We also offer some perspectives on future investigations, providing direction for subsequent research on m(6)A in plants. Elsevier 2023-01-10 /pmc/articles/PMC10203383/ /pubmed/36627844 http://dx.doi.org/10.1016/j.xplc.2023.100546 Text en © 2023. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Tang, Jun
Chen, Shuyan
Jia, Guifang
Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants
title Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants
title_full Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants
title_fullStr Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants
title_full_unstemmed Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants
title_short Detection, regulation, and functions of RNA N(6)-methyladenosine modification in plants
title_sort detection, regulation, and functions of rna n(6)-methyladenosine modification in plants
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203383/
https://www.ncbi.nlm.nih.gov/pubmed/36627844
http://dx.doi.org/10.1016/j.xplc.2023.100546
work_keys_str_mv AT tangjun detectionregulationandfunctionsofrnan6methyladenosinemodificationinplants
AT chenshuyan detectionregulationandfunctionsofrnan6methyladenosinemodificationinplants
AT jiaguifang detectionregulationandfunctionsofrnan6methyladenosinemodificationinplants