Case report: NUDT15 polymorphism and severe azathioprine-induced myelosuppression in a young Chinese female with systematic lupus erythematosus: a case analysis and literature review

Azathioprine is clinically used as an immunosuppressant for treating autoimmune diseases. However it has narrow therapeutic indices due to frequent myelosuppression. Polymorphic variants of genes coding for thiopurine S-methyltransferase (TPMT) and nucleoside diphosphate-linked moiety X motif 15 (NU...

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Detalles Bibliográficos
Autores principales: Gu, Juan, Lin, Yupei, Wang, Yuhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203499/
https://www.ncbi.nlm.nih.gov/pubmed/37229272
http://dx.doi.org/10.3389/fphar.2023.1001559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203499/
https://www.ncbi.nlm.nih.gov/pubmed/37229272
http://dx.doi.org/10.3389/fphar.2023.1001559

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