Cargando…
Selection of biophysically favorable antibody variants using a modified Flp-In CHO mammalian display platform
Mammalian display enables the selection of biophysically favorable antibodies from a large IgG antibody library displayed on the plasma membrane of mammalian cells. We constructed and validated a novel mammalian display platform utilizing the commercially available Flp-In CHO cell line as a starting...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203562/ https://www.ncbi.nlm.nih.gov/pubmed/37229492 http://dx.doi.org/10.3389/fbioe.2023.1170081 |