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Uncovering transcriptomic landscape alterations of CAN-2409 in in vitro and in vivo glioma models

RATIONALE: CAN-2409 is a locally delivered oncolytic therapy, which results in vaccination against the injected tumor. CAN-2409 consists of a non-replicating adenovirus armed with the Herpes virus thymidine kinase, which metabolizes ganciclovir into a phosphorylated nucleotide that is incorporated i...

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Detalles Bibliográficos
Autores principales:	Koch, Marilin S., Zdioruk, Mykola, Nowicki, Michal O., Hoetker, Michael S., Herbert, Zachary T., Barone, Francesca, Tak, Paul P., Chiocca, E. Antonio, Tabatabai, Ghazaleh, Lawler, Sean E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203593/ https://www.ncbi.nlm.nih.gov/pubmed/37228396 http://dx.doi.org/10.3389/fmed.2023.1140352

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