Cargando…

Nephroprotective mechanisms of Rhizoma Chuanxiong and Radix et Rhizoma Rhei against acute renal injury and renal fibrosis based on network pharmacology and experimental validation

The molecular mechanisms of Rhizoma Chuanxiong (Chuanxiong, CX) and Rhei Radix et Rhizoma (Dahuang, DH) in treating acute kidney injury (AKI) and subsequent renal fibrosis (RF) were investigated in this study by applying network pharmacology and experimental validation. The results showed that aloe-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jun, Li, Tonglu, Li, Zongping, Song, Zhiyong, Gong, Xuezhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203597/ https://www.ncbi.nlm.nih.gov/pubmed/37229255 http://dx.doi.org/10.3389/fphar.2023.1154743

Ejemplares similares

Induction of Apoptosis by Metabolites of Rhei Radix et Rhizoma (Da Huang): A Review of the Potential Mechanism in Hepatocellular Carcinoma
por: Jiang, Huanyu, et al.
Publicado: (2022)

Reveal the Antimigraine Mechanism of Chuanxiong Rhizoma and Cyperi Rhizoma Based on the Integrated Analysis of Metabolomics and Network Pharmacology
por: Zhu, Zhiyao, et al.
Publicado: (2022)

Sources, morphology, phytochemistry, pharmacology of Curcumae Longae Rhizoma, Curcumae Radix, and Curcumae Rhizoma: a review of the literature
por: Zhu, Xin, et al.
Publicado: (2023)

Pharmacokinetics effects of chuanxiong rhizoma on warfarin in pseudo germ-free rats
por: Li, Haigang, et al.
Publicado: (2023)

Herbal formula, Scutellariae radix and Rhei rhizoma attenuate dimethylnitrosamine-induced liver fibrosis in a rat model
por: Pan, Tai-Long, et al.
Publicado: (2015)

Phytochemical and Pharmacological Review of Da Chuanxiong Formula: A Famous Herb Pair Composed of Chuanxiong Rhizoma and Gastrodiae Rhizoma for Headache
por: Wang, Lu, et al.
Publicado: (2013)

Antioxidant and Anti-Inflammatory Effects of Rhei Rhizoma and Coptidis Rhizoma Mixture on Reflux Esophagitis in Rats
por: Kwon, O Jun, et al.
Publicado: (2016)

A Tau Pathogenesis-Based Network Pharmacology Approach for Exploring the Protections of Chuanxiong Rhizoma in Alzheimer’s Disease
por: Zeng, Peng, et al.
Publicado: (2022)

Key Phytochemicals and Biological Functions of Chuanxiong Rhizoma Against Ischemic Stroke: A Network Pharmacology and Experimental Assessment
por: Zeng, Peng, et al.
Publicado: (2021)

Exploring the Potential Mechanism of Chuanxiong Rhizoma Treatment for Migraine Based on Systems Pharmacology
por: Wen, Xianhua, et al.
Publicado: (2021)

Rapid Determination of 30 Polyphenols in Tongmai Formula, a Combination of Puerariae Lobatae Radix, Salviae Miltiorrhizae Radix et Rhizoma, and Chuanxiong Rhizoma, via Liquid Chromatography-Tandem Mass Spectrometry
por: Wang, Fu-Rong, et al.
Publicado: (2017)

A Compositive Strategy to Study the Pharmacokinetics of TCMs: Taking Coptidis Rhizoma, and Coptidis Rhizoma-Glycyrrhizae Radix et Rhizoma as Examples
por: Li, Qiao, et al.
Publicado: (2018)

Network Pharmacology and Molecular Docking Analyses of Mechanisms Underlying Effects of the Cyperi Rhizoma-Chuanxiong Rhizoma Herb Pair on Depression
por: Shi, Yanan, et al.
Publicado: (2021)

A Review of the Botany, Phytochemistry, Pharmacology and Toxicology of Rubiae Radix et Rhizoma
por: Shan, Mingqiu, et al.
Publicado: (2016)

Muscle Fatigue-Alleviating Effects of a Prescription Composed of Polygonati Rhizoma and Notoginseng Radix et Rhizoma
por: Yang, Ya-Qin, et al.
Publicado: (2020)

Research on the potential mechanism of Chuanxiong Rhizoma on treating Diabetic Nephropathy based on network pharmacology
por: Hu, Shanshan, et al.
Publicado: (2020)

Metabolomics- and systems toxicology-based hepatotoxicity mechanism of Sophorae Tonkinensis Radix et Rhizoma in rats
por: Yu, Dengxiang, et al.
Publicado: (2022)

Synergistic Effects of Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) Combination in Angiogenesis Behavior in EAhy 926 Cells
por: Zhou, Xian, et al.
Publicado: (2017)

Network Pharmacology-Based Investigation on Therapeutic Mechanisms of the Angelica dahurica Radix and Ligusticum chuanxiong Rhizoma Herb Pair for Anti-Migraine Effect
por: Thanh, Chu Duc, et al.
Publicado: (2022)

Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of “Chuanxiong Rhizoma: Radix Salviae miltiorrhizae” Herb Couples in the Treatment of Preeclampsia
por: Wei, Jing, et al.
Publicado: (2022)

Molecular mechanism of Chuanxiong Rhizoma in treating coronary artery diseases
por: Yin, Bang-qiao, et al.
Publicado: (2021)

Long-chain alkanol–alkyl carboxylic acid-based low-viscosity hydrophobic deep eutectic solvents for one-pot extraction of anthraquinones from Rhei Radix et Rhizoma
por: Huang, Anqi, et al.
Publicado: (2022)

Molecular Mechanisms of Notopterygii rhizoma Et Radix for Treating Arrhythmia Based on Network Pharmacology
por: Wei, Penglu, et al.
Publicado: (2023)

Retracted: Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of “Chuanxiong Rhizoma: Radix Salviae miltiorrhizae” Herb Couples in the Treatment of Preeclampsia
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Synergistic study of a Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination on cell survival in EA.hy926 cells
por: Zhou, Xian, et al.
Publicado: (2019)

Synergistic Effects of Danshen (Salvia Miltiorrhiza Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) Combination in Inhibiting Inflammation Mediators in RAW264.7 Cells
por: Zhou, Xian, et al.
Publicado: (2016)

The mechanisms of Chuanxiong Rhizoma in treating spinal cord injury based on network pharmacology and experimental verification
por: Tao, Bo, et al.
Publicado: (2021)

Systematic review of ethnomedicine, phytochemistry, and pharmacology of Cyperi Rhizoma
por: Wang, Fengyou, et al.
Publicado: (2022)

Detoxification technology and mechanism of processing with Angelicae sinensis radix in reducing the hepatotoxicity induced by rhizoma Dioscoreae bulbiferae in vivo
por: Song, Lingling, et al.
Publicado: (2022)

Lignan and Phthalide Derivatives from the Rhizome of Ligusticum chuanxiong (Rhizoma chuanxiong) and Evaluation of Their anti-Xanthine Oxidase Activities
por: Yang, Man-Li, et al.
Publicado: (2023)

Ethnobotany, phytochemistry and pharmacological properties of Fagopyri Dibotryis Rhizoma: A review
por: Geng, Qi, et al.
Publicado: (2023)

Exploring the Regulatory Mechanism of Hedysarum Multijugum Maxim.-Chuanxiong Rhizoma Compound on HIF-VEGF Pathway and Cerebral Ischemia-Reperfusion Injury’s Biological Network Based on Systematic Pharmacology
por: Yang, Kailin, et al.
Publicado: (2021)

Exploring the Mechanism of Chuanxiong Rhizoma against Thrombosis Based on Network Pharmacology, Molecular Docking and Experimental Verification
por: He, Shasha, et al.
Publicado: (2023)

Anti-Migraine Effect of the Herbal Combination of Chuanxiong Rhizoma and Cyperi Rhizoma and UPLC-MS/MS Method for the Simultaneous Quantification of the Active Constituents in Rat Serum and Cerebral Cortex
por: Wu, Sha, et al.
Publicado: (2019)

Lipidomics Indicates the Hepatotoxicity Effects of EtOAc Extract of Rhizoma Paridis
por: Li, Chaofeng, et al.
Publicado: (2022)

Potential therapeutic effects of Chinese meteria medica in mitigating drug-induced acute kidney injury
por: Li, Jun, et al.
Publicado: (2023)

Effects of Valerianae Radix et Rhizoma extract on psychological stress in mice
por: Kim, Jeong Suk, et al.
Publicado: (2015)

Chronoeffects of the Herbal Medicines Puerariae radix and Coptidis rhizoma in Mice: A Potential Role of REV-ERBα
por: Liu, Jinming, et al.
Publicado: (2021)

Exploring the mechanism of Radix Rhei Et Rhizome intervention in intracerebral hemorrhage based on systematic pharmacology and proteomics strategy
por: Zhu, Xiaofei, et al.
Publicado: (2021)

Mechanism of Radix Rhei Et Rhizome Intervention in Cerebral Infarction: A Research Based on Chemoinformatics and Systematic Pharmacology
por: Xiang, Wang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9mrklkcid6f0aav048gi38v9lv