Cargando…
Investigation of heteroscedasticity in polygenic risk scores across 15 quantitative traits
The polygenic risk score (PRS) could be used to stratify individuals with high risk of diseases and predict complex trait of individual in a population. Previous studies developed a PRS-based prediction model using linear regression and evaluated the predictive performance of the model using the R (...
Autores principales: | Jung, Hyein, Jung, Hae-Un, Baek, Eun Ju, Chung, Ju Yeon, Kwon, Shin Young, Kang, Ji-One, Lim, Ji Eun, Oh, Bermseok |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203621/ https://www.ncbi.nlm.nih.gov/pubmed/37229196 http://dx.doi.org/10.3389/fgene.2023.1150889 |
Ejemplares similares
-
The effect of heteroscedasticity on the prediction efficiency of genome-wide polygenic score for body mass index
por: Baek, Eun Ju, et al.
Publicado: (2022) -
Identification of five genetic variants with differential effects on obesity-related traits based on age
por: Chung, Ju Yeon, et al.
Publicado: (2022) -
Genome-Wide Interaction Study of Late-Onset Asthma With Seven Environmental Factors Using a Structured Linear Mixed Model in Europeans
por: Baek, Eun Ju, et al.
Publicado: (2022) -
Association Between Environmental Factors and Asthma Using Mendelian Randomization: Increased Effect of Body Mass Index on Adult-Onset Moderate-to-Severe Asthma Subtypes
por: Ha, Tae-Woong, et al.
Publicado: (2021) -
Identification of asthma-related genes using asthmatic blood eQTLs of Korean patients
por: Kim, Dong Jun, et al.
Publicado: (2023)