Fatty acid elongases 1-3 have distinct roles in mitochondrial function, growth, and lipid homeostasis in Trypanosoma cruzi

Trypanosomatids are a diverse group of uniflagellate protozoan parasites that include globally relevant pathogens such as Trypanosoma cruzi, the causative agent of Chagas disease. Trypanosomes lack the fatty acid synthase system typically used for de novo fatty acid (FA) synthesis in other eukaryote...

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Detalles Bibliográficos
Autores principales: Pagura, Lucas, Dumoulin, Peter C., Ellis, Cameron C., Mendes, Maria T., Estevao, Igor L., Almeida, Igor C., Burleigh, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203773/
https://www.ncbi.nlm.nih.gov/pubmed/37061002
http://dx.doi.org/10.1016/j.jbc.2023.104715

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