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Infection à Covid-19 en gériatrie au Sénégal

OBJECTIVES: While the elderly incurred high mortality during the Covid-19 pandemic, the geriatric particularities remain little known. The objective of this work was to determine the geriatric specificities, in particular epidemiological, diagnostic and therapeutic, of this infection in Senegal. MET...

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Autores principales: Massamba, B., Assane, Sall, Rokhaya, Djajhete, Dalahata, Ba, Mamadou, Coume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203877/
http://dx.doi.org/10.1016/j.npg.2023.05.005
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author Massamba, B.
Assane, Sall
Rokhaya, Djajhete
Dalahata, Ba
Mamadou, Coume
author_facet Massamba, B.
Assane, Sall
Rokhaya, Djajhete
Dalahata, Ba
Mamadou, Coume
author_sort Massamba, B.
collection PubMed
description OBJECTIVES: While the elderly incurred high mortality during the Covid-19 pandemic, the geriatric particularities remain little known. The objective of this work was to determine the geriatric specificities, in particular epidemiological, diagnostic and therapeutic, of this infection in Senegal. METHODS: This was a retrospective, descriptive, observational study over a period of 13 months (beginning of August 2020 to end of August 2021) conducted in a population of individuals aged 65 years and older admitted to the only university geriatric department in Senegal. Patients infected with COVID-19 confirmed by a positive RT-PCR (reverse transcriptase polymerase chain reaction) and nasal or pharyngeal swabs were included. RESULTS: During this period, out of 215 hospitalized patients, 40 tested positive for Covid-19, a proportion of 18.6%. The mean age of the patients was 79 years (±7), predominantly male (65%). Most patients (45%) came from the hospital emergency department. Frailty concerned 67.5% of the patients and 25% had a chronic loss of autonomy. Clinical signs were dominated by alteration of the general state and pulmonary condensation syndrome, each affecting half of the patients, followed by fever (40%), anorexia (35%), dyspnea (32.5%) and transit disorders (25%). The geriatric syndromes were mainly loss of functional autonomy for 77.5% of the patients, malnutrition for 67.5%, confusional syndrome for 25% and depression for 25%. On the thoracic CT scan, the extent of the lesions was severe for half of the patients with extensive forms for 25% of the patients, severe for 22.5% and critical for 2.5%. All patients received antibiotic therapy based on azithromycin and 57.5% received amoxicillin-clavulanic acid while only 7.5% received hydroxychloroquine. Non-drug treatments were mainly motor rehabilitation for 80% of the patients, nutritional management for 77.5%, supportive psychotherapy for 50% and temporo-spatial reorientation protocols for confusion for 30%. Complications were dominated by acute renal failure (47.5%), ionic disorders (42.5%) and bacterial superinfections (22.5%). The mortality rate was 20%. CONCLUSION: This study, in addition to confirming the atypical nature of the symptomatology and the severity of the pulmonary involvement, has above all highlighted the multidimensional particularities of the geriatric management of Covid-19.
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spelling pubmed-102038772023-05-23 Infection à Covid-19 en gériatrie au Sénégal Massamba, B. Assane, Sall Rokhaya, Djajhete Dalahata, Ba Mamadou, Coume Npg Données Fondamentales OBJECTIVES: While the elderly incurred high mortality during the Covid-19 pandemic, the geriatric particularities remain little known. The objective of this work was to determine the geriatric specificities, in particular epidemiological, diagnostic and therapeutic, of this infection in Senegal. METHODS: This was a retrospective, descriptive, observational study over a period of 13 months (beginning of August 2020 to end of August 2021) conducted in a population of individuals aged 65 years and older admitted to the only university geriatric department in Senegal. Patients infected with COVID-19 confirmed by a positive RT-PCR (reverse transcriptase polymerase chain reaction) and nasal or pharyngeal swabs were included. RESULTS: During this period, out of 215 hospitalized patients, 40 tested positive for Covid-19, a proportion of 18.6%. The mean age of the patients was 79 years (±7), predominantly male (65%). Most patients (45%) came from the hospital emergency department. Frailty concerned 67.5% of the patients and 25% had a chronic loss of autonomy. Clinical signs were dominated by alteration of the general state and pulmonary condensation syndrome, each affecting half of the patients, followed by fever (40%), anorexia (35%), dyspnea (32.5%) and transit disorders (25%). The geriatric syndromes were mainly loss of functional autonomy for 77.5% of the patients, malnutrition for 67.5%, confusional syndrome for 25% and depression for 25%. On the thoracic CT scan, the extent of the lesions was severe for half of the patients with extensive forms for 25% of the patients, severe for 22.5% and critical for 2.5%. All patients received antibiotic therapy based on azithromycin and 57.5% received amoxicillin-clavulanic acid while only 7.5% received hydroxychloroquine. Non-drug treatments were mainly motor rehabilitation for 80% of the patients, nutritional management for 77.5%, supportive psychotherapy for 50% and temporo-spatial reorientation protocols for confusion for 30%. Complications were dominated by acute renal failure (47.5%), ionic disorders (42.5%) and bacterial superinfections (22.5%). The mortality rate was 20%. CONCLUSION: This study, in addition to confirming the atypical nature of the symptomatology and the severity of the pulmonary involvement, has above all highlighted the multidimensional particularities of the geriatric management of Covid-19. Elsevier Masson SAS. 2023-05-23 /pmc/articles/PMC10203877/ http://dx.doi.org/10.1016/j.npg.2023.05.005 Text en © 2023 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Données Fondamentales
Massamba, B.
Assane, Sall
Rokhaya, Djajhete
Dalahata, Ba
Mamadou, Coume
Infection à Covid-19 en gériatrie au Sénégal
title Infection à Covid-19 en gériatrie au Sénégal
title_full Infection à Covid-19 en gériatrie au Sénégal
title_fullStr Infection à Covid-19 en gériatrie au Sénégal
title_full_unstemmed Infection à Covid-19 en gériatrie au Sénégal
title_short Infection à Covid-19 en gériatrie au Sénégal
title_sort infection à covid-19 en gériatrie au sénégal
topic Données Fondamentales
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203877/
http://dx.doi.org/10.1016/j.npg.2023.05.005
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