Cargando…

Biosynthesis of Antifungal Solanimycin May Involve an Iterative Nonribosomal Peptide Synthetase Module

[Image: see text] Dickeya solani, a plant-pathogenic bacterium, produces solanimycin, a potent hybrid polyketide/nonribosomal peptide (PKS/NRPS) anti-fungal compound. The biosynthetic gene cluster responsible for synthesis of this compound has been identified. Because of instability, the complete st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Murphy, Annabel C., Corney, Matthew, Monson, Rita E., Matilla, Miguel A., Salmond, George P. C., Leeper, Finian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204066/ https://www.ncbi.nlm.nih.gov/pubmed/37068480 http://dx.doi.org/10.1021/acschembio.2c00947

Ejemplares similares

Solanimycin: Biosynthesis and Distribution of a New Antifungal Antibiotic Regulated by Two Quorum-Sensing Systems
por: Matilla, Miguel A., et al.
Publicado: (2022)

Fungal siderophore biosynthesis catalysed by an iterative nonribosomal peptide synthetase
por: Hai, Yang, et al.
Publicado: (2020)

Biosynthesis of the antifungal haterumalide, oocydin A, in Serratia, and its regulation by quorum sensing, RpoS and Hfq
por: Matilla, Miguel A, et al.
Publicado: (2015)

Decoding and reprogramming fungal iterative nonribosomal peptide synthetases
por: Yu, Dayu, et al.
Publicado: (2017)

Diversity of Nonribosomal Peptide Synthetases Involved in the Biosynthesis of Lipopeptide Biosurfactants
por: Roongsawang, Niran, et al.
Publicado: (2010)

Nonribosomal Peptide Synthetases in Animals
por: Suring, Wouter, et al.
Publicado: (2023)

Revision in the first steps of the biosynthesis of the red antibiotic prodigiosin: use of a synthetic thioester to validate a new intermediate
por: Couturier, Maxime, et al.
Publicado: (2021)

Phylogenetic Study of Polyketide Synthases and Nonribosomal Peptide Synthetases Involved in the Biosynthesis of Mycotoxins
por: Gallo, Antonia, et al.
Publicado: (2013)

Guidelines for Optimizing Type S Nonribosomal Peptide Synthetases
por: Abbood, Nadya, et al.
Publicado: (2023)

Module evolution and substrate specificity of fungal nonribosomal peptide synthetases involved in siderophore biosynthesis
por: Bushley, Kathryn E, et al.
Publicado: (2008)

Substrate Flexibility of the Flavin‐Dependent Dihydropyrrole Oxidases PigB and HapB Involved in Antibiotic Prodigiosin Biosynthesis
por: Couturier, Maxime, et al.
Publicado: (2019)

Reconstitution of Iterative Thioamidation in Closthioamide Biosynthesis Reveals Tailoring Strategy for Nonribosomal Peptide Backbones
por: Dunbar, Kyle L., et al.
Publicado: (2019)

In Vitro Characterization of a Heterologously Expressed Nonribosomal Peptide Synthetase Involved in Phosphinothricin Tripeptide Biosynthesis
por: Lee, Jin-Hee, et al.
Publicado: (2009)

Nonribosomal peptide synthetases and their biotechnological potential in Penicillium rubens
por: Iacovelli, Riccardo, et al.
Publicado: (2021)

Structures of Two Distinct Conformations of holo-Nonribosomal Peptide Synthetases
por: Drake, Eric J., et al.
Publicado: (2016)

Distribution and Evolution of Nonribosomal Peptide Synthetase Gene Clusters in the Ceratocystidaceae
por: Sayari, Mohammad, et al.
Publicado: (2019)

Correction to: Nonribosomal peptide synthetases and their biotechnological potential in Penicillium rubens
por: Iacovelli, Riccardo, et al.
Publicado: (2022)

Phylogenomics reveals subfamilies of fungal nonribosomal peptide synthetases and their evolutionary relationships
por: Bushley, Kathryn E, et al.
Publicado: (2010)

Diversity of Nonribosomal Peptide Synthetase Genes in the Microbial Metagenomes of Marine Sponges
por: Pimentel-Elardo, Sheila Marie, et al.
Publicado: (2012)

Nonribosomal Peptides Produced by Minimal and Engineered Synthetases with Terminal Reductase Domains
por: Tietze, Andreas, et al.
Publicado: (2020)

Intermediary conformations linked to the directionality of the aminoacylation pathway of nonribosomal peptide synthetases
por: Mayerthaler, Florian, et al.
Publicado: (2021)

Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains()
por: Tan, Kemin, et al.
Publicado: (2020)

Proof-Reading Thioesterase Boosts Activity of Engineered Nonribosomal Peptide Synthetase
por: Pourmasoumi, Farzaneh, et al.
Publicado: (2022)

Methylation-Dependent Acyl Transfer between Polyketide Synthase and Nonribosomal Peptide Synthetase Modules in Fungal Natural Product Biosynthesis
por: Zou, Yi, et al.
Publicado: (2014)

Putative Nonribosomal Peptide Synthetase and Cytochrome P450 Genes Responsible for Tentoxin Biosynthesis in Alternaria alternata ZJ33
por: Li, You-Hai, et al.
Publicado: (2016)

Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker's yeast
por: Awan, Ali R., et al.
Publicado: (2017)

Lincosamide Synthetase—A Unique Condensation System Combining Elements of Nonribosomal Peptide Synthetase and Mycothiol Metabolism
por: Janata, Jiri, et al.
Publicado: (2015)

Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases
por: Götze, Sebastian, et al.
Publicado: (2019)

Characterization of the Ketosynthase and Acyl Carrier Protein Domains at the LnmI Nonribosomal Peptide Synthetase–Polyketide Synthase Interface for Leinamycin Biosynthesis
por: Huang, Yong, et al.
Publicado: (2016)

The Nonribosomal Peptide Valinomycin: From Discovery to Bioactivity and Biosynthesis
por: Huang, Shuhui, et al.
Publicado: (2021)

Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis
por: Zhong, Lin, et al.
Publicado: (2021)

Polyketide Synthase and Nonribosomal Peptide Synthetase Gene Clusters in Type Strains of the Genus Phytohabitans
por: Komaki, Hisayuki, et al.
Publicado: (2020)

Catalytic trajectory of a dimeric nonribosomal peptide synthetase subunit with an inserted epimerase domain
por: Wang, Jialiang, et al.
Publicado: (2022)

Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module
por: Fortinez, Camille Marie, et al.
Publicado: (2022)

Colorimetric Determination of Adenylation Domain Activity in Nonribosomal Peptide Synthetases by Using Chrome Azurol S
por: Kahlert, Lukas, et al.
Publicado: (2023)

Engineering of Specific Single-Module Nonribosomal Peptide Synthetases of the RXP Type for the Production of Defined Peptides
por: Cai, Xiaofeng, et al.
Publicado: (2022)

Biosynthesis and engineering of the nonribosomal peptides with a C-terminal putrescine
por: Chen, Hanna, et al.
Publicado: (2023)

Harnessing fungal nonribosomal cyclodepsipeptide synthetases for mechanistic insights and tailored engineering
por: Steiniger, Charlotte, et al.
Publicado: (2017)

Antimicrobial Peptide Resistance of Vibrio cholerae Results from an LPS Modification Pathway Related to Nonribosomal Peptide Synthetases
por: Henderson, Jeremy C., et al.
Publicado: (2014)

Halogenase Genes in Nonribosomal Peptide Synthetase Gene Clusters of Microcystis (Cyanobacteria): Sporadic Distribution and Evolution
por: Cadel-Six, Sabrina, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_u7c4flndc951k86h23eea4hsfu