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Aprepitant inhibits the development and metastasis of gallbladder cancer via ROS and MAPK activation

BACKGROUND: Aprepitant, as a neurokinin-1 receptor (NK-1R) antagonist, originally applied for curing chemotherapy-induced nausea and vomiting, has been reported to have significant antitumor effect on several malignant tumors. However, the effect of aprepitant on gallbladder cancer (GBC) is not clea...

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Detalles Bibliográficos
Autores principales:	Cao, Xueyan, Yang, Yang, Zhou, Wei, Wang, Yue, Wang, Xue, Ge, Xianxiu, Wang, Fei, Zhou, Fangfang, Deng, Xueting, Miao, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204192/ https://www.ncbi.nlm.nih.gov/pubmed/37221457 http://dx.doi.org/10.1186/s12885-023-10954-8

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