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S100A6 inhibits MDM2 to suppress breast cancer growth and enhance sensitivity to chemotherapy

BACKGROUND: S100A6 and murine double minute 2 (MDM2) are important cancer-related molecules. A previous study identified an interaction between S100A6 and MDM2 by size exclusion chromatography and surface plasmon resonance experiments. The present study investigated whether S100A6 could bind to MDM2...

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Detalles Bibliográficos
Autores principales: Qi, Mengxin, Yi, Xianglan, Yue, Baohui, Huang, Mingxiang, Zhou, Sheng, Xiong, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204293/
https://www.ncbi.nlm.nih.gov/pubmed/37217945
http://dx.doi.org/10.1186/s13058-023-01657-w