Circular RNA Tmcc1 improves astrocytic glutamate metabolism and spatial memory via NF-κB and CREB signaling in a bile duct ligation mouse model: transcriptional and cellular analyses

BACKGROUND: Hepatic encephalopathy-induced hyperammonemia alters astrocytic glutamate metabolism in the brain, which is involved in cognitive decline. To identify specific therapeutic strategies for the treatment of hepatic encephalopathy, various molecular signaling studies, such as non-coding RNA...

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Detalles Bibliográficos
Autores principales: Jo, Danbi, Lim, Yeong-Hwan, Jung, Yoon Seok, Kim, Young-Kook, Song, Juhyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204305/
https://www.ncbi.nlm.nih.gov/pubmed/37217942
http://dx.doi.org/10.1186/s12974-023-02806-w

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