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Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa

BACKGROUND: In Gabon, malaria remains a major public health problem. All malaria cases with axillary temperature ≥ 37.5°C with a parasites density ≥ 1200/μL are serious cases and must be treated as a medical emergency. Thus, early diagnosis is essential for successful treatment. Because of the impac...

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Autores principales: Boundenga, Larson, Bignoumba, Michelle, Dibakou, Serge-Ely, Mombo, Landry Erik, Moukagni-Mussadji, Clauve Jauvert, Wora, Dorothé Marielle, Kassa-Kassa, Fabrice, Bisseye, Cyrille, Onanga, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204601/
https://www.ncbi.nlm.nih.gov/pubmed/37229438
http://dx.doi.org/10.4081/jphia.2023.1865
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author Boundenga, Larson
Bignoumba, Michelle
Dibakou, Serge-Ely
Mombo, Landry Erik
Moukagni-Mussadji, Clauve Jauvert
Wora, Dorothé Marielle
Kassa-Kassa, Fabrice
Bisseye, Cyrille
Onanga, Richard
author_facet Boundenga, Larson
Bignoumba, Michelle
Dibakou, Serge-Ely
Mombo, Landry Erik
Moukagni-Mussadji, Clauve Jauvert
Wora, Dorothé Marielle
Kassa-Kassa, Fabrice
Bisseye, Cyrille
Onanga, Richard
author_sort Boundenga, Larson
collection PubMed
description BACKGROUND: In Gabon, malaria remains a major public health problem. All malaria cases with axillary temperature ≥ 37.5°C with a parasites density ≥ 1200/μL are serious cases and must be treated as a medical emergency. Thus, early diagnosis is essential for successful treatment. Because of the impact of malaria on the population, the surveillance of malaria infections in hospitals is urgently needed. The aim of this study was to to assess of clinical cases of malaria in a private health structure in Franceville between 2017 and 2019. METHODS: For that, we conducted a retrospective study using data on malaria cases recorded in a private medical analysis laboratory in Franceville, southeast Gabon. Malaria was diagnosed in this laboratory using a Rapid Diagnostic Test and confirmed by microscopic analysis. RESULTS: Analysis of 2518 patient forms revealed an increase in malaria prevalence in Franceville between 2017-2019. The global clinical cases was 26.1% (658/2015). Children under 5 years (44.0%) and patients aged 5-14 years (40.1%) were more affected than patients aged ≥15 years (18.8%, P=0.0001). Malaria infection was also significantly dependent on season and gender. We observed at least three Plasmodium species and the predominant Plasmodium species was P. falciparum 80.0%, followed by P. ovale (19.5%) and P. malariae (17.8%). CONCLUSION: Our study showed that malaria remains a public health priority for the population of Franceville and that the prevalence of clinical cases of malaria at the laboratory decrease between 2017 and 2019. Our results highlight the need for strategies to control malaria in Franceville, adapted to epidemiological contexts and environmental constraint.
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spelling pubmed-102046012023-05-24 Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa Boundenga, Larson Bignoumba, Michelle Dibakou, Serge-Ely Mombo, Landry Erik Moukagni-Mussadji, Clauve Jauvert Wora, Dorothé Marielle Kassa-Kassa, Fabrice Bisseye, Cyrille Onanga, Richard J Public Health Afr Article BACKGROUND: In Gabon, malaria remains a major public health problem. All malaria cases with axillary temperature ≥ 37.5°C with a parasites density ≥ 1200/μL are serious cases and must be treated as a medical emergency. Thus, early diagnosis is essential for successful treatment. Because of the impact of malaria on the population, the surveillance of malaria infections in hospitals is urgently needed. The aim of this study was to to assess of clinical cases of malaria in a private health structure in Franceville between 2017 and 2019. METHODS: For that, we conducted a retrospective study using data on malaria cases recorded in a private medical analysis laboratory in Franceville, southeast Gabon. Malaria was diagnosed in this laboratory using a Rapid Diagnostic Test and confirmed by microscopic analysis. RESULTS: Analysis of 2518 patient forms revealed an increase in malaria prevalence in Franceville between 2017-2019. The global clinical cases was 26.1% (658/2015). Children under 5 years (44.0%) and patients aged 5-14 years (40.1%) were more affected than patients aged ≥15 years (18.8%, P=0.0001). Malaria infection was also significantly dependent on season and gender. We observed at least three Plasmodium species and the predominant Plasmodium species was P. falciparum 80.0%, followed by P. ovale (19.5%) and P. malariae (17.8%). CONCLUSION: Our study showed that malaria remains a public health priority for the population of Franceville and that the prevalence of clinical cases of malaria at the laboratory decrease between 2017 and 2019. Our results highlight the need for strategies to control malaria in Franceville, adapted to epidemiological contexts and environmental constraint. PAGEPress Publications, Pavia, Italy 2023-05-04 /pmc/articles/PMC10204601/ /pubmed/37229438 http://dx.doi.org/10.4081/jphia.2023.1865 Text en ©Copyright: the Author(s), https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Boundenga, Larson
Bignoumba, Michelle
Dibakou, Serge-Ely
Mombo, Landry Erik
Moukagni-Mussadji, Clauve Jauvert
Wora, Dorothé Marielle
Kassa-Kassa, Fabrice
Bisseye, Cyrille
Onanga, Richard
Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa
title Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa
title_full Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa
title_fullStr Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa
title_full_unstemmed Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa
title_short Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa
title_sort decrease on malaria clinical cases from 2017 to 2019 in franceville, southeast gabon, central africa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204601/
https://www.ncbi.nlm.nih.gov/pubmed/37229438
http://dx.doi.org/10.4081/jphia.2023.1865
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