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Durvalumab plus tremelimumab for the treatment of advanced neuroendocrine neoplasms of gastroenteropancreatic and lung origin
Single immune checkpoint blockade in advanced neuroendocrine neoplasms (NENs) shows limited efficacy; dual checkpoint blockade may improve treatment activity. Dune (NCT03095274) is a non-randomized controlled multicohort phase II clinical trial evaluating durvalumab plus tremelimumab activity and sa...
Autores principales: | Capdevila, J., Hernando, J., Teule, A., Lopez, C., Garcia-Carbonero, R., Benavent, M., Custodio, A., Garcia-Alvarez, A., Cubillo, A., Alonso, V., Carmona-Bayonas, A., Alonso-Gordoa, T., Crespo, G., Jimenez-Fonseca, P., Blanco, M., Viudez, A., La Casta, A., Sevilla, I., Segura, A., Llanos, M., Landolfi, S., Nuciforo, P., Manzano, J. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204675/ https://www.ncbi.nlm.nih.gov/pubmed/37221181 http://dx.doi.org/10.1038/s41467-023-38611-5 |
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