Differential Eye Expression of Xenopus Acyltransferase Gnpat and Its Biochemical Characterization Shed Light on Lipid-Associated Ocular Pathologies

PURPOSE: Plasmalogens (Plgs) are highly abundant lipids in the retina, and their deficiency leads to severe abnormalities during eye development. The first acylation step in the synthesis of Plgs is catalyzed by the enzyme glyceronephosphate O-acyltransferase (GNPAT), which is also known as dihydrox...

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Detalles Bibliográficos
Autores principales: Bertolesi, Gabriel E., Chilije, Maxwell F. J., Li, Victoria, Thompson, Chase C., López-Villalobos, Arturo, Hehr, Carrie L., Atkinson-Leadbeater, Karen, Zaremberg, Vanina, McFarlane, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204775/
https://www.ncbi.nlm.nih.gov/pubmed/37204785
http://dx.doi.org/10.1167/iovs.64.5.17

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