Cargando…

Акромегалия при дифференциальной диагностике тугоухости

Acromegaly is a multifactorial neuroendocrine disease caused by hyperproduction of growth hormone (GH). In more than 95% of cases the reason of acromegaly the GH-secreting pituitary adenoma. In patients with this neuroendocrine disease, a slowly developing complex of symptom can manifest with concom...

Descripción completa

Detalles Bibliográficos
Autores principales: Дзеранова, Л. К., Лепешкина, Л. И., Шутова, А. С., Перепелова, М. А., Пигарова, Е. А., Азизян, В. Н., Акопян, П. В., Пржиялковская, Е. Г., Мельниченко, Г. А., Мокрышева, Н. Г.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrinology Research Centre 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204780/
https://www.ncbi.nlm.nih.gov/pubmed/37448269
http://dx.doi.org/10.14341/probl13249
_version_ 1785045903858466816
author Дзеранова, Л. К.
Лепешкина, Л. И.
Шутова, А. С.
Перепелова, М. А.
Пигарова, Е. А.
Азизян, В. Н.
Акопян, П. В.
Пржиялковская, Е. Г.
Мельниченко, Г. А.
Мокрышева, Н. Г.
author_facet Дзеранова, Л. К.
Лепешкина, Л. И.
Шутова, А. С.
Перепелова, М. А.
Пигарова, Е. А.
Азизян, В. Н.
Акопян, П. В.
Пржиялковская, Е. Г.
Мельниченко, Г. А.
Мокрышева, Н. Г.
author_sort Дзеранова, Л. К.
collection PubMed
description Acromegaly is a multifactorial neuroendocrine disease caused by hyperproduction of growth hormone (GH). In more than 95% of cases the reason of acromegaly the GH-secreting pituitary adenoma. In patients with this neuroendocrine disease, a slowly developing complex of symptom can manifest with concomitant pathological conditions, including auditory function disordersDiagnostic difficulties of acromegaly at the ambulatory stage determine the importance of doctor`s awareness in different medical specialties. Here we demonstrate a clinical case of the improvement of the auditory function due to combined surgical and medical treatment of a patient with the pituitary macroadenoma, acromegaly and hearing loss. Anamnesis features: a patient with an active stage of acromegaly and a pituitary macroadenoma measuring 57x35x32 mm with ante-, supra-, infra-, parasellar spread, (Knosp III(D), Knosp IV(S) noted a violation of auditory function. She was consulted by an otolaryngologist, sensorineural hearing loss on the right of the 3rd degree was diagnosed, on the left of the 1st degree. The patient underwent surgical treatment of pituitary adenoma, noted a significant improvement in auditory function in the early postoperative period. Six months later, repeated audiometry was performed, marked regression of hearing damage was noted. The case described by us indicates the reversibility of a rare complication of acromegaly — hearing loss and the importance of an interdisciplinary approach in the management of patients with this pathology.
format Online
Article
Text
id pubmed-10204780
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Endocrinology Research Centre
record_format MEDLINE/PubMed
spelling pubmed-102047802023-05-24 Акромегалия при дифференциальной диагностике тугоухости Дзеранова, Л. К. Лепешкина, Л. И. Шутова, А. С. Перепелова, М. А. Пигарова, Е. А. Азизян, В. Н. Акопян, П. В. Пржиялковская, Е. Г. Мельниченко, Г. А. Мокрышева, Н. Г. Probl Endokrinol (Mosk) Research Article Acromegaly is a multifactorial neuroendocrine disease caused by hyperproduction of growth hormone (GH). In more than 95% of cases the reason of acromegaly the GH-secreting pituitary adenoma. In patients with this neuroendocrine disease, a slowly developing complex of symptom can manifest with concomitant pathological conditions, including auditory function disordersDiagnostic difficulties of acromegaly at the ambulatory stage determine the importance of doctor`s awareness in different medical specialties. Here we demonstrate a clinical case of the improvement of the auditory function due to combined surgical and medical treatment of a patient with the pituitary macroadenoma, acromegaly and hearing loss. Anamnesis features: a patient with an active stage of acromegaly and a pituitary macroadenoma measuring 57x35x32 mm with ante-, supra-, infra-, parasellar spread, (Knosp III(D), Knosp IV(S) noted a violation of auditory function. She was consulted by an otolaryngologist, sensorineural hearing loss on the right of the 3rd degree was diagnosed, on the left of the 1st degree. The patient underwent surgical treatment of pituitary adenoma, noted a significant improvement in auditory function in the early postoperative period. Six months later, repeated audiometry was performed, marked regression of hearing damage was noted. The case described by us indicates the reversibility of a rare complication of acromegaly — hearing loss and the importance of an interdisciplinary approach in the management of patients with this pathology. Endocrinology Research Centre 2023-05-11 /pmc/articles/PMC10204780/ /pubmed/37448269 http://dx.doi.org/10.14341/probl13249 Text en Copyright © Endocrinology Research Centre, 2023 https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 License.
spellingShingle Research Article
Дзеранова, Л. К.
Лепешкина, Л. И.
Шутова, А. С.
Перепелова, М. А.
Пигарова, Е. А.
Азизян, В. Н.
Акопян, П. В.
Пржиялковская, Е. Г.
Мельниченко, Г. А.
Мокрышева, Н. Г.
Акромегалия при дифференциальной диагностике тугоухости
title Акромегалия при дифференциальной диагностике тугоухости
title_full Акромегалия при дифференциальной диагностике тугоухости
title_fullStr Акромегалия при дифференциальной диагностике тугоухости
title_full_unstemmed Акромегалия при дифференциальной диагностике тугоухости
title_short Акромегалия при дифференциальной диагностике тугоухости
title_sort акромегалия при дифференциальной диагностике тугоухости
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204780/
https://www.ncbi.nlm.nih.gov/pubmed/37448269
http://dx.doi.org/10.14341/probl13249
work_keys_str_mv AT dzeranovalk akromegaliâpridifferencialʹnojdiagnostiketugouhosti
AT lepeškinali akromegaliâpridifferencialʹnojdiagnostiketugouhosti
AT šutovaas akromegaliâpridifferencialʹnojdiagnostiketugouhosti
AT perepelovama akromegaliâpridifferencialʹnojdiagnostiketugouhosti
AT pigarovaea akromegaliâpridifferencialʹnojdiagnostiketugouhosti
AT azizânvn akromegaliâpridifferencialʹnojdiagnostiketugouhosti
AT akopânpv akromegaliâpridifferencialʹnojdiagnostiketugouhosti
AT pržiâlkovskaâeg akromegaliâpridifferencialʹnojdiagnostiketugouhosti
AT melʹničenkoga akromegaliâpridifferencialʹnojdiagnostiketugouhosti
AT mokryševang akromegaliâpridifferencialʹnojdiagnostiketugouhosti