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Relation of impulse oscillometry and spirometry with quantitative thorax computed tomography after COVID-19 pneumonia
OBJECTIVE: This study aimed to investigate if there is any correlation between the quantitative computed tomography and the impulse oscillometry or spirometry results of post-COVID-19 patients. METHODS: The study comprised 47 post-COVID-19 patients who had spirometry, impulse oscillometry, and high-...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Médica Brasileira
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204846/ https://www.ncbi.nlm.nih.gov/pubmed/37222321 http://dx.doi.org/10.1590/1806-9282.20221427 |
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author | Sahin, Mustafa Engin Gökçek, Atila Satar, Seher Ergün, Pınar |
author_facet | Sahin, Mustafa Engin Gökçek, Atila Satar, Seher Ergün, Pınar |
author_sort | Sahin, Mustafa Engin |
collection | PubMed |
description | OBJECTIVE: This study aimed to investigate if there is any correlation between the quantitative computed tomography and the impulse oscillometry or spirometry results of post-COVID-19 patients. METHODS: The study comprised 47 post-COVID-19 patients who had spirometry, impulse oscillometry, and high-resolution computed tomography examinations at the same time. The study group consisted of 33 patients with quantitative computed tomography involvement, while the control group included 14 patients who did not have CT findings. The quantitative computed tomography technology was used to calculate percentages of density range volumes. The relationship between percentages of density range volumes for different quantitative computed tomography density ranges and impulse oscillometry-spirometry findings was statistically analyzed. RESULTS: In quantitative computed tomography, the percentage of relatively high-density lung parenchyma, including fibrotic areas, was 1.76±0.43 and 5.65±3.73 in the control and study groups, respectively. The percentages of primarily ground-glass parenchyma areas were found to be 7.60±2.86 and 29.25±16.50 in the control and study groups, respectively. In the correlation analysis, the forced vital capacity% predicted in the study group was correlated with DRV%([(-750)-(-500)]) (volume of the lung parenchyma that has density between (-750)-(-500) Hounsfield units), but no correlation with DRV%([(-500)-0]) was detected. Also, reactance area and resonant frequency were correlated with DRV%([(-750)-(-500)]), while X(5) was correlated with both DRV%([(-500)-0]) and DRV%([(-750)-(-500)]) density. Modified Medical Research Council score was correlated with predicted percentages of forced vital capacity and X(5). CONCLUSION: After COVID-19, forced vital capacity, reactance area, resonant frequency, and X(5) correlated with the percentages of density range volumes of ground-glass opacity areas in the quantitative computed tomography. X(5) was the only parameter correlated with density ranges consistent with both ground-glass opacity and fibrosis. Furthermore, the percentages of forced vital capacity and X(5) were shown to be associated with the perception of dyspnea. |
format | Online Article Text |
id | pubmed-10204846 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Associação Médica Brasileira |
record_format | MEDLINE/PubMed |
spelling | pubmed-102048462023-05-24 Relation of impulse oscillometry and spirometry with quantitative thorax computed tomography after COVID-19 pneumonia Sahin, Mustafa Engin Gökçek, Atila Satar, Seher Ergün, Pınar Rev Assoc Med Bras (1992) Original Article OBJECTIVE: This study aimed to investigate if there is any correlation between the quantitative computed tomography and the impulse oscillometry or spirometry results of post-COVID-19 patients. METHODS: The study comprised 47 post-COVID-19 patients who had spirometry, impulse oscillometry, and high-resolution computed tomography examinations at the same time. The study group consisted of 33 patients with quantitative computed tomography involvement, while the control group included 14 patients who did not have CT findings. The quantitative computed tomography technology was used to calculate percentages of density range volumes. The relationship between percentages of density range volumes for different quantitative computed tomography density ranges and impulse oscillometry-spirometry findings was statistically analyzed. RESULTS: In quantitative computed tomography, the percentage of relatively high-density lung parenchyma, including fibrotic areas, was 1.76±0.43 and 5.65±3.73 in the control and study groups, respectively. The percentages of primarily ground-glass parenchyma areas were found to be 7.60±2.86 and 29.25±16.50 in the control and study groups, respectively. In the correlation analysis, the forced vital capacity% predicted in the study group was correlated with DRV%([(-750)-(-500)]) (volume of the lung parenchyma that has density between (-750)-(-500) Hounsfield units), but no correlation with DRV%([(-500)-0]) was detected. Also, reactance area and resonant frequency were correlated with DRV%([(-750)-(-500)]), while X(5) was correlated with both DRV%([(-500)-0]) and DRV%([(-750)-(-500)]) density. Modified Medical Research Council score was correlated with predicted percentages of forced vital capacity and X(5). CONCLUSION: After COVID-19, forced vital capacity, reactance area, resonant frequency, and X(5) correlated with the percentages of density range volumes of ground-glass opacity areas in the quantitative computed tomography. X(5) was the only parameter correlated with density ranges consistent with both ground-glass opacity and fibrosis. Furthermore, the percentages of forced vital capacity and X(5) were shown to be associated with the perception of dyspnea. Associação Médica Brasileira 2023-05-19 /pmc/articles/PMC10204846/ /pubmed/37222321 http://dx.doi.org/10.1590/1806-9282.20221427 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Sahin, Mustafa Engin Gökçek, Atila Satar, Seher Ergün, Pınar Relation of impulse oscillometry and spirometry with quantitative thorax computed tomography after COVID-19 pneumonia |
title | Relation of impulse oscillometry and spirometry with quantitative thorax computed tomography after COVID-19 pneumonia |
title_full | Relation of impulse oscillometry and spirometry with quantitative thorax computed tomography after COVID-19 pneumonia |
title_fullStr | Relation of impulse oscillometry and spirometry with quantitative thorax computed tomography after COVID-19 pneumonia |
title_full_unstemmed | Relation of impulse oscillometry and spirometry with quantitative thorax computed tomography after COVID-19 pneumonia |
title_short | Relation of impulse oscillometry and spirometry with quantitative thorax computed tomography after COVID-19 pneumonia |
title_sort | relation of impulse oscillometry and spirometry with quantitative thorax computed tomography after covid-19 pneumonia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204846/ https://www.ncbi.nlm.nih.gov/pubmed/37222321 http://dx.doi.org/10.1590/1806-9282.20221427 |
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