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Interleukin-11 disrupts alveolar epithelial progenitor function

BACKGROUND: Interleukin-11 (IL-11) is linked to the pathogenesis of idiopathic pulmonary fibrosis (IPF), since IL-11 induces myofibroblast differentiation and stimulates their excessive collagen deposition in the lung. In IPF there is disrupted alveolar structural architecture, yet the effect of IL-...

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Detalles Bibliográficos
Autores principales:	Kortekaas, Rosa K., Geillinger-Kästle, Kerstin E., Borghuis, Theo, Belharch, Kaoutar, Webster, Megan, Timens, Wim, Burgess, Janette K., Gosens, Reinoud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Respiratory Society 2023
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204861/ https://www.ncbi.nlm.nih.gov/pubmed/37228276 http://dx.doi.org/10.1183/23120541.00679-2022

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