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Clinical Profile and Predictors of Early Outcome in Patients with Traumatic Spinal Cord Injury in Jos, North-Central Nigeria

BACKGROUND/OBJECTIVES: Spinal cord injury is a devastating condition and has been recognised so since antiquity with evolving pattern of presentation and outcome. This study aimed to review the clinical profile and determinants of early outcome in patients with traumatic spinal cord injury (TSCI) in...

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Autores principales: Alfin, Jeneral Dumura, Shilong, Danaan Joseph, Bot, Gyang Markus, Nwibo, Onyemaechi Ereke, Kyesmen, Nanpan Isa, Olalere, Shina Abidemi, Bakwa, Nenkimun Dirting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204922/
https://www.ncbi.nlm.nih.gov/pubmed/37228886
http://dx.doi.org/10.4103/jwas.jwas_200_22
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author Alfin, Jeneral Dumura
Shilong, Danaan Joseph
Bot, Gyang Markus
Nwibo, Onyemaechi Ereke
Kyesmen, Nanpan Isa
Olalere, Shina Abidemi
Bakwa, Nenkimun Dirting
author_facet Alfin, Jeneral Dumura
Shilong, Danaan Joseph
Bot, Gyang Markus
Nwibo, Onyemaechi Ereke
Kyesmen, Nanpan Isa
Olalere, Shina Abidemi
Bakwa, Nenkimun Dirting
author_sort Alfin, Jeneral Dumura
collection PubMed
description BACKGROUND/OBJECTIVES: Spinal cord injury is a devastating condition and has been recognised so since antiquity with evolving pattern of presentation and outcome. This study aimed to review the clinical profile and determinants of early outcome in patients with traumatic spinal cord injury (TSCI) in Jos, Nigeria. MATERIALS AND METHODS: This retrospective cohort study, reviewed the health records of all patients with TSCI that were managed, based on the neurosurgical unit protocol for the management of TSCI in our institution from 2011 to 2021. Relevant data were retrieved into a preformed pro forma, analysis was done for determinants of outcome using SPSS and presented in tables and figure. RESULTS: A total of 296 patients, aged 20–39 years, with male to female ratio of 5.2:1 were studied. The median time from injury to presentation was 96 h, and the cervical spine was the most (139, 47.0%) affected region. Most of the patients (183, 61.8%) had complete injury (ASIA A) at presentation, the average, first week mean arterial blood pressure (MAP) of 89.98 ± 8.86. Mortality was 73 (24.7%) at 6 weeks post injury and complete TSCI, cervical spinal cord segment and the average “first week” MAP were, independent predictors of mortality. The admission ASIA impairment scale (AIS) and injury to presentation interval were predictive of AIS improvement at 6 weeks and length of hospital stay (LOHs). CONCLUSIONS: We also found that AIS at admission, level of spinal cord affected and the average first week MAP were early predictors of mortality, while the injury to presentation interval and admission AIS, predicted improvement of AIS at 6 weeks. The LOHs was seen more in patients with severe AIS at admission and those who had delayed presentation.
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spelling pubmed-102049222023-05-24 Clinical Profile and Predictors of Early Outcome in Patients with Traumatic Spinal Cord Injury in Jos, North-Central Nigeria Alfin, Jeneral Dumura Shilong, Danaan Joseph Bot, Gyang Markus Nwibo, Onyemaechi Ereke Kyesmen, Nanpan Isa Olalere, Shina Abidemi Bakwa, Nenkimun Dirting J West Afr Coll Surg Original Article BACKGROUND/OBJECTIVES: Spinal cord injury is a devastating condition and has been recognised so since antiquity with evolving pattern of presentation and outcome. This study aimed to review the clinical profile and determinants of early outcome in patients with traumatic spinal cord injury (TSCI) in Jos, Nigeria. MATERIALS AND METHODS: This retrospective cohort study, reviewed the health records of all patients with TSCI that were managed, based on the neurosurgical unit protocol for the management of TSCI in our institution from 2011 to 2021. Relevant data were retrieved into a preformed pro forma, analysis was done for determinants of outcome using SPSS and presented in tables and figure. RESULTS: A total of 296 patients, aged 20–39 years, with male to female ratio of 5.2:1 were studied. The median time from injury to presentation was 96 h, and the cervical spine was the most (139, 47.0%) affected region. Most of the patients (183, 61.8%) had complete injury (ASIA A) at presentation, the average, first week mean arterial blood pressure (MAP) of 89.98 ± 8.86. Mortality was 73 (24.7%) at 6 weeks post injury and complete TSCI, cervical spinal cord segment and the average “first week” MAP were, independent predictors of mortality. The admission ASIA impairment scale (AIS) and injury to presentation interval were predictive of AIS improvement at 6 weeks and length of hospital stay (LOHs). CONCLUSIONS: We also found that AIS at admission, level of spinal cord affected and the average first week MAP were early predictors of mortality, while the injury to presentation interval and admission AIS, predicted improvement of AIS at 6 weeks. The LOHs was seen more in patients with severe AIS at admission and those who had delayed presentation. Wolters Kluwer - Medknow 2023 2023-03-20 /pmc/articles/PMC10204922/ /pubmed/37228886 http://dx.doi.org/10.4103/jwas.jwas_200_22 Text en Copyright: © 2023 Journal of the West African College of Surgeons https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Alfin, Jeneral Dumura
Shilong, Danaan Joseph
Bot, Gyang Markus
Nwibo, Onyemaechi Ereke
Kyesmen, Nanpan Isa
Olalere, Shina Abidemi
Bakwa, Nenkimun Dirting
Clinical Profile and Predictors of Early Outcome in Patients with Traumatic Spinal Cord Injury in Jos, North-Central Nigeria
title Clinical Profile and Predictors of Early Outcome in Patients with Traumatic Spinal Cord Injury in Jos, North-Central Nigeria
title_full Clinical Profile and Predictors of Early Outcome in Patients with Traumatic Spinal Cord Injury in Jos, North-Central Nigeria
title_fullStr Clinical Profile and Predictors of Early Outcome in Patients with Traumatic Spinal Cord Injury in Jos, North-Central Nigeria
title_full_unstemmed Clinical Profile and Predictors of Early Outcome in Patients with Traumatic Spinal Cord Injury in Jos, North-Central Nigeria
title_short Clinical Profile and Predictors of Early Outcome in Patients with Traumatic Spinal Cord Injury in Jos, North-Central Nigeria
title_sort clinical profile and predictors of early outcome in patients with traumatic spinal cord injury in jos, north-central nigeria
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204922/
https://www.ncbi.nlm.nih.gov/pubmed/37228886
http://dx.doi.org/10.4103/jwas.jwas_200_22
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