Assessing SARS-CoV-2-specific T-cell reactivity in late convalescents and vaccinees: Comparison and combination of QuantiFERON and activation-induced marker assays, and relation with antibody status

OBJECTIVES: Monitoring of SARS-CoV-2 spread and vaccination strategies have relied on antibody (Ab) status as a correlate of protection. We used QuantiFERON™ (QFN) and Activation-Induced Marker (AIM) assays to measure memory T-cell reactivity in unvaccinated individuals with prior documented symptom...

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Detalles Bibliográficos
Autores principales: Gatti, Arianna, Zizzo, Gaetano, De Paschale, Massimo, Tamburello, Antonio, Castelnovo, Laura, Faggioli, Paola Maria, Clerici, Pierangelo, Brando, Bruno, Mazzone, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204942/
https://www.ncbi.nlm.nih.gov/pubmed/37220145
http://dx.doi.org/10.1371/journal.pone.0285728

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