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The Lack of Natural IgM Increases Susceptibility and Impairs Anti-Vi Polysaccharide IgG Responses in a Mouse Model of Typhoid

Circulating IgM present in the body prior to any apparent Ag exposure is referred to as natural IgM. Natural IgM provides protective immunity against a variety of pathogens. Salmonella enterica serovar Typhi (S. Typhi) is the causative agent of typhoid fever in humans. Because mice are not permissiv...

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Detalles Bibliográficos
Autores principales:	Alugupalli, Akhil S., Cravens, Matthew P., Walker, Justin A., Gulandijany, Dania, Dickinson, Gregory S., Debes, Gudrun F., Schifferli, Dieter M., Bäumler, Andreas J., Alugupalli, Kishore R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205010/ https://www.ncbi.nlm.nih.gov/pubmed/36480484 http://dx.doi.org/10.4049/immunohorizons.2200088

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