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Marijuana as a Cause of Diffuse Coronary Vasospasm Leading to Cardiac Arrest

Marijuana is considered as the most popular illicit drug around the world. It has numerous cardiovascular effects with myocardial infarction (MI) being a lethal one. The negative physiological effects of marijuana are well-studied, including tachycardia, nausea, memory impairment, anxiety, panic, an...

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Autores principales: Khan, Muhammad Atif, Khan, Faiza Humayun, Khan, Hina Benish, Brabham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205149/
https://www.ncbi.nlm.nih.gov/pubmed/37228539
http://dx.doi.org/10.7759/cureus.38026
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author Khan, Muhammad Atif
Khan, Faiza Humayun
Khan, Hina Benish
Brabham, David
author_facet Khan, Muhammad Atif
Khan, Faiza Humayun
Khan, Hina Benish
Brabham, David
author_sort Khan, Muhammad Atif
collection PubMed
description Marijuana is considered as the most popular illicit drug around the world. It has numerous cardiovascular effects with myocardial infarction (MI) being a lethal one. The negative physiological effects of marijuana are well-studied, including tachycardia, nausea, memory impairment, anxiety, panic, and arrhythmia. We present a case of cardiac arrest following marijuana use in a patient who had a normal electrocardiogram (EKG) on presentation but diffuse coronary vasospasm on left heart catheterization (LHC) with no obstructive lesion. The patient had a transient episode of ST elevation on EKG following the procedure which resolved with an increased dose of nitroglycerine drip. Synthetic cannabinoids are more potent and not detected on a regular urine drug screen (UDS). In patients with low risk for cardiovascular events, particularly young adults, presenting with symptoms of MI/cardiac arrest, marijuana-induced MI should be suspected due to the severe adverse effects of its synthetic component. 
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spelling pubmed-102051492023-05-24 Marijuana as a Cause of Diffuse Coronary Vasospasm Leading to Cardiac Arrest Khan, Muhammad Atif Khan, Faiza Humayun Khan, Hina Benish Brabham, David Cureus Cardiology Marijuana is considered as the most popular illicit drug around the world. It has numerous cardiovascular effects with myocardial infarction (MI) being a lethal one. The negative physiological effects of marijuana are well-studied, including tachycardia, nausea, memory impairment, anxiety, panic, and arrhythmia. We present a case of cardiac arrest following marijuana use in a patient who had a normal electrocardiogram (EKG) on presentation but diffuse coronary vasospasm on left heart catheterization (LHC) with no obstructive lesion. The patient had a transient episode of ST elevation on EKG following the procedure which resolved with an increased dose of nitroglycerine drip. Synthetic cannabinoids are more potent and not detected on a regular urine drug screen (UDS). In patients with low risk for cardiovascular events, particularly young adults, presenting with symptoms of MI/cardiac arrest, marijuana-induced MI should be suspected due to the severe adverse effects of its synthetic component.  Cureus 2023-04-23 /pmc/articles/PMC10205149/ /pubmed/37228539 http://dx.doi.org/10.7759/cureus.38026 Text en Copyright © 2023, Khan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Khan, Muhammad Atif
Khan, Faiza Humayun
Khan, Hina Benish
Brabham, David
Marijuana as a Cause of Diffuse Coronary Vasospasm Leading to Cardiac Arrest
title Marijuana as a Cause of Diffuse Coronary Vasospasm Leading to Cardiac Arrest
title_full Marijuana as a Cause of Diffuse Coronary Vasospasm Leading to Cardiac Arrest
title_fullStr Marijuana as a Cause of Diffuse Coronary Vasospasm Leading to Cardiac Arrest
title_full_unstemmed Marijuana as a Cause of Diffuse Coronary Vasospasm Leading to Cardiac Arrest
title_short Marijuana as a Cause of Diffuse Coronary Vasospasm Leading to Cardiac Arrest
title_sort marijuana as a cause of diffuse coronary vasospasm leading to cardiac arrest
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205149/
https://www.ncbi.nlm.nih.gov/pubmed/37228539
http://dx.doi.org/10.7759/cureus.38026
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