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Hurthle cell carcinoma: a rare variant of thyroid malignancy – a case report
Oncocytic/Hurthle cell neoplasm is a rare form of thyroid malignancies, derived from follicular epithelium, presenting with a wide variety having either presenting with features of thyrotoxicosis or no any associated symptoms. CASE PRESENTATION: The authors present a case of a 49-year-old female wit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205327/ https://www.ncbi.nlm.nih.gov/pubmed/37229083 http://dx.doi.org/10.1097/MS9.0000000000000456 |
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author | Adhikari, Yuvraj Marasini, Anupama Adhikari, Nawaraj Paneru, Laxman D. Upadhaya Regmi, Binit Raut, Manita |
author_facet | Adhikari, Yuvraj Marasini, Anupama Adhikari, Nawaraj Paneru, Laxman D. Upadhaya Regmi, Binit Raut, Manita |
author_sort | Adhikari, Yuvraj |
collection | PubMed |
description | Oncocytic/Hurthle cell neoplasm is a rare form of thyroid malignancies, derived from follicular epithelium, presenting with a wide variety having either presenting with features of thyrotoxicosis or no any associated symptoms. CASE PRESENTATION: The authors present a case of a 49-year-old female with a known case of chronic obstructive pulmonary disease and hypertension who presented to our hospital with anterior neck swelling for 4 months that has gradually increased over the time. Physical examination, laboratory test, various radiological imaging, and cytological study led to the diagnosis of Hurthle cell neoplasm. With prompt diagnosis, she was admitted and surgery was done that include right hemithyroidectomy. Though it is a rare type of thyroid malignancy, early diagnosis and proper treatment has shown a very good prognosis. CLINICAL DISCUSSION: Hurthle cell carcinoma initially presents with a single, painless palpable mass in the thyroid with pressure symptoms in advanced cases including dysphagia, dyspnea, and hoarseness. Pain, rapid growth, or significant compressive symptoms are suggestive of an invasive one. CONCLUSION: This case highlights on rarity of disease, presentation, and availability of treatment modality. |
format | Online Article Text |
id | pubmed-10205327 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-102053272023-05-24 Hurthle cell carcinoma: a rare variant of thyroid malignancy – a case report Adhikari, Yuvraj Marasini, Anupama Adhikari, Nawaraj Paneru, Laxman D. Upadhaya Regmi, Binit Raut, Manita Ann Med Surg (Lond) Case Reports Oncocytic/Hurthle cell neoplasm is a rare form of thyroid malignancies, derived from follicular epithelium, presenting with a wide variety having either presenting with features of thyrotoxicosis or no any associated symptoms. CASE PRESENTATION: The authors present a case of a 49-year-old female with a known case of chronic obstructive pulmonary disease and hypertension who presented to our hospital with anterior neck swelling for 4 months that has gradually increased over the time. Physical examination, laboratory test, various radiological imaging, and cytological study led to the diagnosis of Hurthle cell neoplasm. With prompt diagnosis, she was admitted and surgery was done that include right hemithyroidectomy. Though it is a rare type of thyroid malignancy, early diagnosis and proper treatment has shown a very good prognosis. CLINICAL DISCUSSION: Hurthle cell carcinoma initially presents with a single, painless palpable mass in the thyroid with pressure symptoms in advanced cases including dysphagia, dyspnea, and hoarseness. Pain, rapid growth, or significant compressive symptoms are suggestive of an invasive one. CONCLUSION: This case highlights on rarity of disease, presentation, and availability of treatment modality. Lippincott Williams & Wilkins 2023-04-05 /pmc/articles/PMC10205327/ /pubmed/37229083 http://dx.doi.org/10.1097/MS9.0000000000000456 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Case Reports Adhikari, Yuvraj Marasini, Anupama Adhikari, Nawaraj Paneru, Laxman D. Upadhaya Regmi, Binit Raut, Manita Hurthle cell carcinoma: a rare variant of thyroid malignancy – a case report |
title | Hurthle cell carcinoma: a rare variant of thyroid malignancy – a case report |
title_full | Hurthle cell carcinoma: a rare variant of thyroid malignancy – a case report |
title_fullStr | Hurthle cell carcinoma: a rare variant of thyroid malignancy – a case report |
title_full_unstemmed | Hurthle cell carcinoma: a rare variant of thyroid malignancy – a case report |
title_short | Hurthle cell carcinoma: a rare variant of thyroid malignancy – a case report |
title_sort | hurthle cell carcinoma: a rare variant of thyroid malignancy – a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205327/ https://www.ncbi.nlm.nih.gov/pubmed/37229083 http://dx.doi.org/10.1097/MS9.0000000000000456 |
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