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Endobronchial mucormycosis diagnosed by fiberoptic bronchoscopy

INTRODUCTION: Endobronchial mucormycosis is very rare with only few cases reported in the literature. Here, we report a rare presentation of pulmonary mucormycosis in a diabetic patient who presented with left lung collapse. Bronchoscopy revealed an endobronchial growth, mimicking a tumor, causing c...

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Autores principales: Assal, Hebatallah Hany, Hussein, Sabah Ahmed, Mostafa, Ahmed, El-Kareem, Dalia Abd, Alfishawy, Mostafa, Salah, Maged, Mohammed, Habiballah Galal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205427/
https://www.ncbi.nlm.nih.gov/pubmed/37229281
http://dx.doi.org/10.1016/j.idcr.2023.e01781
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author Assal, Hebatallah Hany
Hussein, Sabah Ahmed
Mostafa, Ahmed
El-Kareem, Dalia Abd
Alfishawy, Mostafa
Salah, Maged
Mohammed, Habiballah Galal
author_facet Assal, Hebatallah Hany
Hussein, Sabah Ahmed
Mostafa, Ahmed
El-Kareem, Dalia Abd
Alfishawy, Mostafa
Salah, Maged
Mohammed, Habiballah Galal
author_sort Assal, Hebatallah Hany
collection PubMed
description INTRODUCTION: Endobronchial mucormycosis is very rare with only few cases reported in the literature. Here, we report a rare presentation of pulmonary mucormycosis in a diabetic patient who presented with left lung collapse. Bronchoscopy revealed an endobronchial growth, mimicking a tumor, causing complete occlusion of the left main bronchus. Histopathology confirmed the diagnosis of invasive mucormycosis. CASE PRESENTATION: Male patient 35 years old with accidental discovered Diabetes Mellitus, complained of hoarseness of voice and dry irritating cough that didn’t respond to antitussives and nonspecific treatment. CT chest was done and revealed left total lung collapse. Fiberoptic bronchoscopy was done and revealed total occlusion of the left main bronchus with whitish fungating glistening tissue from which biopsies were obtained. Histopathological examination was consistent with mucormycosis. A trial of medical treatment failed after which the patient was referred for surgical resection. CONCLUSION: Successful treatment of mucormycosis requires early diagnosis; prompt administration of antifungal therapy, and surgical intervention when applicable. Aggressive surgical intervention to remove necrotic tissue is generally accepted as the therapeutic mainstay for endobronchial obstructing mucormycosis
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spelling pubmed-102054272023-05-24 Endobronchial mucormycosis diagnosed by fiberoptic bronchoscopy Assal, Hebatallah Hany Hussein, Sabah Ahmed Mostafa, Ahmed El-Kareem, Dalia Abd Alfishawy, Mostafa Salah, Maged Mohammed, Habiballah Galal IDCases Case Report INTRODUCTION: Endobronchial mucormycosis is very rare with only few cases reported in the literature. Here, we report a rare presentation of pulmonary mucormycosis in a diabetic patient who presented with left lung collapse. Bronchoscopy revealed an endobronchial growth, mimicking a tumor, causing complete occlusion of the left main bronchus. Histopathology confirmed the diagnosis of invasive mucormycosis. CASE PRESENTATION: Male patient 35 years old with accidental discovered Diabetes Mellitus, complained of hoarseness of voice and dry irritating cough that didn’t respond to antitussives and nonspecific treatment. CT chest was done and revealed left total lung collapse. Fiberoptic bronchoscopy was done and revealed total occlusion of the left main bronchus with whitish fungating glistening tissue from which biopsies were obtained. Histopathological examination was consistent with mucormycosis. A trial of medical treatment failed after which the patient was referred for surgical resection. CONCLUSION: Successful treatment of mucormycosis requires early diagnosis; prompt administration of antifungal therapy, and surgical intervention when applicable. Aggressive surgical intervention to remove necrotic tissue is generally accepted as the therapeutic mainstay for endobronchial obstructing mucormycosis Elsevier 2023-05-12 /pmc/articles/PMC10205427/ /pubmed/37229281 http://dx.doi.org/10.1016/j.idcr.2023.e01781 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Assal, Hebatallah Hany
Hussein, Sabah Ahmed
Mostafa, Ahmed
El-Kareem, Dalia Abd
Alfishawy, Mostafa
Salah, Maged
Mohammed, Habiballah Galal
Endobronchial mucormycosis diagnosed by fiberoptic bronchoscopy
title Endobronchial mucormycosis diagnosed by fiberoptic bronchoscopy
title_full Endobronchial mucormycosis diagnosed by fiberoptic bronchoscopy
title_fullStr Endobronchial mucormycosis diagnosed by fiberoptic bronchoscopy
title_full_unstemmed Endobronchial mucormycosis diagnosed by fiberoptic bronchoscopy
title_short Endobronchial mucormycosis diagnosed by fiberoptic bronchoscopy
title_sort endobronchial mucormycosis diagnosed by fiberoptic bronchoscopy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205427/
https://www.ncbi.nlm.nih.gov/pubmed/37229281
http://dx.doi.org/10.1016/j.idcr.2023.e01781
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