CNS toxoplasmosis, a rare presentation in a patient with Myasthenia Gravis

We report the case of a 78-year-old man with a past medical history of non-Hodgkin’s lymphoma s/p chemotherapy and Myasthenia Gravis on chronic mycophenolate mofetil (MMF), who presented with altered mental status and was found to have ring enhancing brain lesions. A brain biopsy revealed organisms...

Descripción completa

Detalles Bibliográficos
Autores principales: King, Rachel, Sekar, Poorani, Patel, Henna, Naveed, Maryam, Aqtash, Sumaia, Adroja, Shubham, Jacob, Denise, Riaz, Talha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205443/
https://www.ncbi.nlm.nih.gov/pubmed/37229280
http://dx.doi.org/10.1016/j.idcr.2023.e01780
Descripción
Sumario:We report the case of a 78-year-old man with a past medical history of non-Hodgkin’s lymphoma s/p chemotherapy and Myasthenia Gravis on chronic mycophenolate mofetil (MMF), who presented with altered mental status and was found to have ring enhancing brain lesions. A brain biopsy revealed organisms consistent with Toxoplasma gondii. Cerebral toxoplasmosis has been rarely reported in patients with hematologic malignancies or in those receiving immunosuppressive agents. There needs to be a high degree of suspicion for T. gondii in HIV-negative individuals who are on immunosuppressants drugs including MMF.

Ejemplares similares