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Development and clinical application of a liquid chromatography-tandem mass spectrometry-based assay to quantify eight tyrosine kinase inhibitors in human plasma

INTRODUCTION: Tyrosine kinase inhibitors (TKIs) are widely used in tumor treatment. The detection of these medicines by liquid chromatography-tandem mass spectrometry (LC-MS/MS) can avoid the interference of structurally similar compounds. OBJECTIVES: This study aimed to develop and validate a new L...

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Detalles Bibliográficos
Autores principales:	Chen, Fangjun, Chen, Wenda, Wang, Zhenxin, Peng, Yingfei, Wang, Beili, Pan, Baishen, Guo, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205537/ https://www.ncbi.nlm.nih.gov/pubmed/37234251 http://dx.doi.org/10.1016/j.jmsacl.2023.05.001

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