Gas therapy potentiates aggregation-induced emission luminogen-based photoimmunotherapy of poorly immunogenic tumors through cGAS-STING pathway activation

The immunologically “cold” microenvironment of triple negative breast cancer results in resistance to current immunotherapy. Here, we reveal the immunoadjuvant property of gas therapy with cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway activation to augment aggregation-i...

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Detalles Bibliográficos
Autores principales: Wang, Kaiyuan, Li, Yang, Wang, Xia, Zhang, Zhijun, Cao, Liping, Fan, Xiaoyuan, Wan, Bin, Liu, Fengxiang, Zhang, Xuanbo, He, Zhonggui, Zhou, Yingtang, Wang, Dong, Sun, Jin, Chen, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205712/
https://www.ncbi.nlm.nih.gov/pubmed/37221157
http://dx.doi.org/10.1038/s41467-023-38601-7

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