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Trogocytic molting of T cell microvilli upregulates T cell receptor surface expression and promotes clonal expansion

Although T cell activation is known to involve the internalization of the T cell antigen receptor (TCR), much less is known regarding the release of TCRs following T cell interaction with cognate antigen-presenting cells. In this study, we examine the physiological mechanisms underlying TCR release...

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Detalles Bibliográficos
Autores principales: Park, Jeong-Su, Kim, Jun-Hyeong, Soh, Won-Chang, Kim, Na-Young, Lee, Kyung-Sik, Kim, Chang-Hyun, Chung, Ik-Joo, Lee, Sunjae, Kim, Hye-Ran, Jun, Chang-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205730/
https://www.ncbi.nlm.nih.gov/pubmed/37221214
http://dx.doi.org/10.1038/s41467-023-38707-y

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