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Poly (ADP-ribose) polymerases 16 triggers pathological cardiac hypertrophy via activating IRE1α–sXBP1–GATA4 pathway

BACKGROUND: Pressure overload-induced pathological cardiac hypertrophy is an independent predecessor of heart failure (HF), which remains the leading cause of worldwide mortality. However, current evidence on the molecular determinants of pathological cardiac hypertrophy is still inadequacy. This st...

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Detalles Bibliográficos
Autores principales: Su, Haibi, Xu, Jie, Su, Zhenghua, Xiao, Chenxi, Wang, Jinghuan, Zhong, Wen, Meng, Chen, Yang, Di, Zhu, Yizhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205867/
https://www.ncbi.nlm.nih.gov/pubmed/37219631
http://dx.doi.org/10.1007/s00018-023-04805-9