Isotretinoin treatment upregulates the expression of p53 in the skin and sebaceous glands of patients with acne vulgaris

The transcriptomic regulation induced by isotretinoin (13-cis retinoic acid) is still a matter of debate as short-term exposures of immortalized sebocytes with isotretinoin produced conflicting results. Based on translational evidence, it has been hypothesized that oral isotretinoin treatment upregu...

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Detalles Bibliográficos
Autores principales: Agamia, Naglaa Fathi, El Mulla, Khalid Fawzi, Alsayed, Naglaa Mohamed, Ghazala, Rasha Mohamed, El Maksoud, Rania Elsayed Abdel, Abdelmeniem, Iman Mohamed, Talaat, Iman Mamdouh, Zaki, Inass Ibrahim, Sabah, Rana Mohamed, Melnik, Bodo Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205870/
https://www.ncbi.nlm.nih.gov/pubmed/36585988
http://dx.doi.org/10.1007/s00403-022-02508-y

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