Fatty acid synthase as a new therapeutic target for HER2-positive gastric cancer

PURPOSE: Trastuzumab is an HER2-specific agent approved as the gold-standard therapy for advanced HER2-positive (HER2+) gastric cancer (GC), but the high rate and rapid appearance of resistance limit its clinical efficacy, resulting in the need to identify new vulnerabilities. Defining the drivers i...

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Detalles Bibliográficos
Autores principales: Castagnoli, Lorenzo, Corso, Simona, Franceschini, Alma, Raimondi, Alessandra, Bellomo, Sara Erika, Dugo, Matteo, Morano, Federica, Prisciandaro, Michele, Brich, Silvia, Belfiore, Antonino, Vingiani, Andrea, Di Bartolomeo, Maria, Pruneri, Giancarlo, Tagliabue, Elda, Giordano, Silvia, Pietrantonio, Filippo, Pupa, Serenella M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205874/
https://www.ncbi.nlm.nih.gov/pubmed/36753044
http://dx.doi.org/10.1007/s13402-023-00769-x

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