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Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication

Hantaviruses are causing life-threatening zoonotic infections in humans. Their tripartite negative-stranded RNA genome is replicated by the multi-functional viral RNA-dependent RNA-polymerase. Here we describe the structure of the Hantaan virus polymerase core and establish conditions for in vitro r...

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Detalles Bibliográficos
Autores principales:	Durieux Trouilleton, Quentin, Barata-García, Sergio, Arragain, Benoît, Reguera, Juan, Malet, Hélène
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206067/ https://www.ncbi.nlm.nih.gov/pubmed/37221161 http://dx.doi.org/10.1038/s41467-023-38555-w

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