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Sting and p53 DNA repair pathways are compromised in Alzheimer’s disease
Alzheimer’s disease (AD) is the most common cause of dementia. A common finding in AD is DNA damage. Double-strand DNA breaks (DSBs) are particularly hazardous to neurons because their post-mitotic state forces neurons to rely on error-prone and potentially mutagenic mechanisms to repair DNA breaks....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206146/ https://www.ncbi.nlm.nih.gov/pubmed/37221295 http://dx.doi.org/10.1038/s41598-023-35533-6 |