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Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis
Genes Sdr16c5 and Sdr16c6 encode proteins that belong to a superfamily of short-chain dehydrogenases/reductases (SDR16C5 and SDR16C6). Simultaneous inactivation of these genes in double-KO (DKO) mice was previously shown to result in a marked enlargement of the mouse Meibomian glands (MGs) and sebac...
Autores principales: | Butovich, Igor A., Wilkerson, Amber, Goggans, Kelli R., Belyaeva, Olga V., Kedishvili, Natalia Y., Yuksel, Seher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206187/ https://www.ncbi.nlm.nih.gov/pubmed/37075844 http://dx.doi.org/10.1016/j.jbc.2023.104725 |
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