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Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis

Genes Sdr16c5 and Sdr16c6 encode proteins that belong to a superfamily of short-chain dehydrogenases/reductases (SDR16C5 and SDR16C6). Simultaneous inactivation of these genes in double-KO (DKO) mice was previously shown to result in a marked enlargement of the mouse Meibomian glands (MGs) and sebac...

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Detalles Bibliográficos
Autores principales: Butovich, Igor A., Wilkerson, Amber, Goggans, Kelli R., Belyaeva, Olga V., Kedishvili, Natalia Y., Yuksel, Seher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206187/
https://www.ncbi.nlm.nih.gov/pubmed/37075844
http://dx.doi.org/10.1016/j.jbc.2023.104725

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