β-Nicotinamide mononucleotide activates NAD+/SIRT1 pathway and attenuates inflammatory and oxidative responses in the hippocampus regions of septic mice

Sepsis-associated encephalopathy (SAE) is one of the common serious complications in sepsis, and the pathogenesis of SAE remains unclear. Sirtuin 1 (SIRT1) has been reported to be downregulated in the hippocampus and SIRT1 agonists can attenuated the cognitive dysfunction in septic mice. Nicotinamid...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Hui-ru, Liu, Qiang, Zhu, Cheng-long, Sun, Xiao-yang, Sun, Chen-yan, Yu, Chang-meng, Li, Peng, Deng, Xiao-ming, Wang, Jia-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206198/
https://www.ncbi.nlm.nih.gov/pubmed/37201414
http://dx.doi.org/10.1016/j.redox.2023.102745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206198/
https://www.ncbi.nlm.nih.gov/pubmed/37201414
http://dx.doi.org/10.1016/j.redox.2023.102745

Ejemplares similares