Characterization of pharmacogenomic variants in a Brazilian admixed cohort of elderly individuals based on whole-genome sequencing data

Introduction: Research in the field of pharmacogenomics (PGx) aims to identify genetic variants that modulate response to drugs, through alterations in their pharmacokinetics (PK) or pharmacodynamics (PD). The distribution of PGx variants differs considerably among populations, and whole-genome sequ...

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Detalles Bibliográficos
Autores principales: Bertholim-Nasciben, Luciana, Scliar, Marilia O., Debortoli, Guilherme, Thiruvahindrapuram, Bhooma, Scherer, Stephen W., Duarte, Yeda A. O., Zatz, Mayana, Suarez-Kurtz, Guilherme, Parra, Esteban J., Naslavsky, Michel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206227/
https://www.ncbi.nlm.nih.gov/pubmed/37234706
http://dx.doi.org/10.3389/fphar.2023.1178715

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