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Enhancing gastric cancer conventional chemotherapy effects by triple angiokinase inhibitor nintedanib in preclinical models

BACKGROUND: Gastric adenocarcinoma (GAC) is the fourth leading cause of cancer death worldwide. Systemic chemotherapy is a preferred treatment option for advanced and recurrent GAC, but response rates and survival prolongation remain limited. Tumor angiogenesis plays a critical role in GAC growth, i...

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Detalles Bibliográficos
Autores principales: Awasthi, Niranjan, Schwarz, Margaret A., Kaurich, Quinn, Zhang, Changhua, Hilberg, Frank, Schwarz, Roderich E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206228/
https://www.ncbi.nlm.nih.gov/pubmed/37234980
http://dx.doi.org/10.3389/fonc.2023.1145999