A global genetic interaction network by single-cell imaging and machine learning

Cellular and organismal phenotypes are controlled by complex gene regulatory networks. However, reference maps of gene function are still scarce across different organisms. Here, we generated synthetic genetic interaction and cell morphology profiles of more than 6,800 genes in cultured Drosophila c...

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Detalles Bibliográficos
Autores principales: Heigwer, Florian, Scheeder, Christian, Bageritz, Josephine, Yousefian, Schayan, Rauscher, Benedikt, Laufer, Christina, Beneyto-Calabuig, Sergi, Funk, Maja Christina, Peters, Vera, Boulougouri, Maria, Bilanovic, Jana, Miersch, Thilo, Schmitt, Barbara, Blass, Claudia, Port, Fillip, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206407/
https://www.ncbi.nlm.nih.gov/pubmed/37116498
http://dx.doi.org/10.1016/j.cels.2023.03.003

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