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Discovery of new pyridine heterocyclic hybrids; design, synthesis, dynamic simulations, and in vitro and in vivo breast cancer biological assays

Pyridine is a nitrogen bearing heterocyclic scaffold that shows a wide range of biological activities. The pyridine nucleus has become an interesting target for medicinal chemistry researchers worldwide. Several pyridine derivatives exhibited good anticancer effects against diverse cell lines. There...

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Detalles Bibliográficos
Autores principales: Abdelshaheed, Menna M., El Subbagh, Hussein I., Tantawy, Mohamed A., Attia, Reem T., Youssef, Khairia M., Fawzy, Iten M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206482/
https://www.ncbi.nlm.nih.gov/pubmed/37235111
http://dx.doi.org/10.1039/d3ra02875e