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Epistasis and evolution: recent advances and an outlook for prediction

As organisms evolve, the effects of mutations change as a result of epistatic interactions with other mutations accumulated along the line of descent. This can lead to shifts in adaptability or robustness that ultimately shape subsequent evolution. Here, we review recent advances in measuring, model...

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Detalles Bibliográficos
Autores principales: Johnson, Milo S., Reddy, Gautam, Desai, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206586/
https://www.ncbi.nlm.nih.gov/pubmed/37226182
http://dx.doi.org/10.1186/s12915-023-01585-3