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A Case of Diabetic Ketoacidosis Presented With Severe Rhabdomyolysis-Induced Acute Kidney Injury

We present a patient who presented with diabetic ketoacidosis and severe rhabdomyolysis-induced acute kidney injury. The patient developed generalized edema, nausea, and vomiting, and his kidney function deteriorated, necessitating renal replacement therapy, despite the successful treatment of his i...

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Autores principales: Amin, Toka, Nassar, Mahmoud, Abosheaishaa, Hazem, Ali, Amr, Zirkiyeva, Milana, Lopez, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206602/
https://www.ncbi.nlm.nih.gov/pubmed/37228554
http://dx.doi.org/10.7759/cureus.38042
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author Amin, Toka
Nassar, Mahmoud
Abosheaishaa, Hazem
Ali, Amr
Zirkiyeva, Milana
Lopez, Ricardo
author_facet Amin, Toka
Nassar, Mahmoud
Abosheaishaa, Hazem
Ali, Amr
Zirkiyeva, Milana
Lopez, Ricardo
author_sort Amin, Toka
collection PubMed
description We present a patient who presented with diabetic ketoacidosis and severe rhabdomyolysis-induced acute kidney injury. The patient developed generalized edema, nausea, and vomiting, and his kidney function deteriorated, necessitating renal replacement therapy, despite the successful treatment of his initial conditions. A comprehensive evaluation was conducted to determine the underlying cause of the severe rhabdomyolysis, including autoimmune myopathies, viral infections, and metabolic disorders. A muscle biopsy revealed necrosis and myophagocytosis but no significant inflammation or myositis. The patient's clinical and laboratory results improved with appropriate treatment, including temporary dialysis and erythropoietin therapy, and he was discharged to continue his rehabilitation with home health care.
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spelling pubmed-102066022023-05-24 A Case of Diabetic Ketoacidosis Presented With Severe Rhabdomyolysis-Induced Acute Kidney Injury Amin, Toka Nassar, Mahmoud Abosheaishaa, Hazem Ali, Amr Zirkiyeva, Milana Lopez, Ricardo Cureus Endocrinology/Diabetes/Metabolism We present a patient who presented with diabetic ketoacidosis and severe rhabdomyolysis-induced acute kidney injury. The patient developed generalized edema, nausea, and vomiting, and his kidney function deteriorated, necessitating renal replacement therapy, despite the successful treatment of his initial conditions. A comprehensive evaluation was conducted to determine the underlying cause of the severe rhabdomyolysis, including autoimmune myopathies, viral infections, and metabolic disorders. A muscle biopsy revealed necrosis and myophagocytosis but no significant inflammation or myositis. The patient's clinical and laboratory results improved with appropriate treatment, including temporary dialysis and erythropoietin therapy, and he was discharged to continue his rehabilitation with home health care. Cureus 2023-04-24 /pmc/articles/PMC10206602/ /pubmed/37228554 http://dx.doi.org/10.7759/cureus.38042 Text en Copyright © 2023, Amin et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Amin, Toka
Nassar, Mahmoud
Abosheaishaa, Hazem
Ali, Amr
Zirkiyeva, Milana
Lopez, Ricardo
A Case of Diabetic Ketoacidosis Presented With Severe Rhabdomyolysis-Induced Acute Kidney Injury
title A Case of Diabetic Ketoacidosis Presented With Severe Rhabdomyolysis-Induced Acute Kidney Injury
title_full A Case of Diabetic Ketoacidosis Presented With Severe Rhabdomyolysis-Induced Acute Kidney Injury
title_fullStr A Case of Diabetic Ketoacidosis Presented With Severe Rhabdomyolysis-Induced Acute Kidney Injury
title_full_unstemmed A Case of Diabetic Ketoacidosis Presented With Severe Rhabdomyolysis-Induced Acute Kidney Injury
title_short A Case of Diabetic Ketoacidosis Presented With Severe Rhabdomyolysis-Induced Acute Kidney Injury
title_sort case of diabetic ketoacidosis presented with severe rhabdomyolysis-induced acute kidney injury
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206602/
https://www.ncbi.nlm.nih.gov/pubmed/37228554
http://dx.doi.org/10.7759/cureus.38042
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