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In vivo KCNQ1-suppression-replacement gene therapy in transgenic rabbits with type 1 long QT syndrome

FUNDING ACKNOWLEDGEMENTS: Type of funding sources: Private company. Main funding source(s): Pfizer BACKGROUND: Type 1 long QT syndrome (LQT1) is a genetic channelopathy characterized by both haploinsufficient and dominant-negative loss-of-function pathogenic variants in the KCNQ1-encoded Kv7.1 K+ ch...

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Detalles Bibliográficos
Autores principales:	Giammarino, L, Nimani, S, Bains, S, Alerni, N, Tester, D J, Christoforou, N, Louradour, J, Jurgensen, J, Barry, M A, Koren, G, Zehender, M, Brunner, M, Brooks, G, Ackerman, M J, Odening, K E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	41.4.5 - Ion Channels, Electrophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206659/ http://dx.doi.org/10.1093/europace/euad122.594

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