Cargando…
Omnipolar technology in ventricular tachycardia ablation: activation and substrate mapping with late activation isochrone analysis under extrastimulus protocol
FUNDING ACKNOWLEDGEMENTS: Type of funding sources: None. INTRODUCTION: The cornerstone of the ablation of eschar-related ventricular tachycardias (VT) is the circumscription of the scar dense zone (DZ)/border zone (BZ) and the identification of regions of slow decremental conduction. The anisotropy...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207052/ http://dx.doi.org/10.1093/europace/euad122.311 |
_version_ | 1785046363927478272 |
---|---|
author | Cabrera Borrego, E Sancez Millan, P Constan De La Revilla, E Tercedor Sanchez, L Alvarez Lopez, M |
author_facet | Cabrera Borrego, E Sancez Millan, P Constan De La Revilla, E Tercedor Sanchez, L Alvarez Lopez, M |
author_sort | Cabrera Borrego, E |
collection | PubMed |
description | FUNDING ACKNOWLEDGEMENTS: Type of funding sources: None. INTRODUCTION: The cornerstone of the ablation of eschar-related ventricular tachycardias (VT) is the circumscription of the scar dense zone (DZ)/border zone (BZ) and the identification of regions of slow decremental conduction. The anisotropy of the BZ generates depolarisation waves with rapid changes in their direction that may not be detected by bipolar electrodes, as their identification capacity is orientation-dependent. Omnipolar technology detects the direction and velocity of the wavefront regardless of its orientation. PURPOSE: Describe the effectiveness of the use of omnipolar technology for the development of electroanatomical and activation maps during the study of VT related to scar. METHODS: Single-centre, observational, descriptive study of a serie of patients: - Patient 1- 72-year-old male with ischaemic heart disease. - Patient 2- 46-year-old male with left arrhythmogenic cardiomyopathy. - Patient 3- 60-year-old male with biventricular arrhythmogenic cardiomyopathy. - Patient 4- 28-year-old female with right arrhythmogenic cardiomyopathy. - Patient 5- 42-year-old male with non-ischemic dilated cardiomyopathy. - Patient 6 - 73-year-old male with arrhythmogenic right cardiomyopathy. Omnipolar technology was used for the creation, under sensed extrastimuli in right ventricular apex protocol, of a voltage map, isochrone late activation map (ILAM), slow decremental conduction (SDC) analysis and, in case of VT induction, activation map with real-time visualisation of conduction vectors ("Strategic-multielectrode-positioning" / StaMP-mapping). RESULTS: In patients 1, 2 and 3 ILAM was performed identifying SDC regions. After induction of VT, StaMP-mapping was performed in these regions with identification of the diastolic corridor (image 1A, 1B, 1C). The corridor was eliminated and, subsequently, arrhythmogenic substrate ablation of late potentials in DZ/BZ was performed. In patients 4, 5 and 6 an identical protocol was performed, but VT induction was not achieved, so substrate ablation strategy was performed (image 1D, 1E, 1F). Patient 6 has had a recurrence of sustained VT. CONCLUSIONS: Omnipolar technology, associated with the extrastimulus protocol, allows a more accurate study of scar-related VT, through the identification of SDC regions. These locations are current targets for substrate ablation and, in many cases, the origin of the critical isthmus. [Figure: see text] |
format | Online Article Text |
id | pubmed-10207052 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-102070522023-05-25 Omnipolar technology in ventricular tachycardia ablation: activation and substrate mapping with late activation isochrone analysis under extrastimulus protocol Cabrera Borrego, E Sancez Millan, P Constan De La Revilla, E Tercedor Sanchez, L Alvarez Lopez, M Europace 13.4.3 - Ablation of Ventricular Arrhythmias FUNDING ACKNOWLEDGEMENTS: Type of funding sources: None. INTRODUCTION: The cornerstone of the ablation of eschar-related ventricular tachycardias (VT) is the circumscription of the scar dense zone (DZ)/border zone (BZ) and the identification of regions of slow decremental conduction. The anisotropy of the BZ generates depolarisation waves with rapid changes in their direction that may not be detected by bipolar electrodes, as their identification capacity is orientation-dependent. Omnipolar technology detects the direction and velocity of the wavefront regardless of its orientation. PURPOSE: Describe the effectiveness of the use of omnipolar technology for the development of electroanatomical and activation maps during the study of VT related to scar. METHODS: Single-centre, observational, descriptive study of a serie of patients: - Patient 1- 72-year-old male with ischaemic heart disease. - Patient 2- 46-year-old male with left arrhythmogenic cardiomyopathy. - Patient 3- 60-year-old male with biventricular arrhythmogenic cardiomyopathy. - Patient 4- 28-year-old female with right arrhythmogenic cardiomyopathy. - Patient 5- 42-year-old male with non-ischemic dilated cardiomyopathy. - Patient 6 - 73-year-old male with arrhythmogenic right cardiomyopathy. Omnipolar technology was used for the creation, under sensed extrastimuli in right ventricular apex protocol, of a voltage map, isochrone late activation map (ILAM), slow decremental conduction (SDC) analysis and, in case of VT induction, activation map with real-time visualisation of conduction vectors ("Strategic-multielectrode-positioning" / StaMP-mapping). RESULTS: In patients 1, 2 and 3 ILAM was performed identifying SDC regions. After induction of VT, StaMP-mapping was performed in these regions with identification of the diastolic corridor (image 1A, 1B, 1C). The corridor was eliminated and, subsequently, arrhythmogenic substrate ablation of late potentials in DZ/BZ was performed. In patients 4, 5 and 6 an identical protocol was performed, but VT induction was not achieved, so substrate ablation strategy was performed (image 1D, 1E, 1F). Patient 6 has had a recurrence of sustained VT. CONCLUSIONS: Omnipolar technology, associated with the extrastimulus protocol, allows a more accurate study of scar-related VT, through the identification of SDC regions. These locations are current targets for substrate ablation and, in many cases, the origin of the critical isthmus. [Figure: see text] Oxford University Press 2023-05-24 /pmc/articles/PMC10207052/ http://dx.doi.org/10.1093/europace/euad122.311 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | 13.4.3 - Ablation of Ventricular Arrhythmias Cabrera Borrego, E Sancez Millan, P Constan De La Revilla, E Tercedor Sanchez, L Alvarez Lopez, M Omnipolar technology in ventricular tachycardia ablation: activation and substrate mapping with late activation isochrone analysis under extrastimulus protocol |
title | Omnipolar technology in ventricular tachycardia ablation: activation and substrate mapping with late activation isochrone analysis under extrastimulus protocol |
title_full | Omnipolar technology in ventricular tachycardia ablation: activation and substrate mapping with late activation isochrone analysis under extrastimulus protocol |
title_fullStr | Omnipolar technology in ventricular tachycardia ablation: activation and substrate mapping with late activation isochrone analysis under extrastimulus protocol |
title_full_unstemmed | Omnipolar technology in ventricular tachycardia ablation: activation and substrate mapping with late activation isochrone analysis under extrastimulus protocol |
title_short | Omnipolar technology in ventricular tachycardia ablation: activation and substrate mapping with late activation isochrone analysis under extrastimulus protocol |
title_sort | omnipolar technology in ventricular tachycardia ablation: activation and substrate mapping with late activation isochrone analysis under extrastimulus protocol |
topic | 13.4.3 - Ablation of Ventricular Arrhythmias |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207052/ http://dx.doi.org/10.1093/europace/euad122.311 |
work_keys_str_mv | AT cabreraborregoe omnipolartechnologyinventriculartachycardiaablationactivationandsubstratemappingwithlateactivationisochroneanalysisunderextrastimulusprotocol AT sancezmillanp omnipolartechnologyinventriculartachycardiaablationactivationandsubstratemappingwithlateactivationisochroneanalysisunderextrastimulusprotocol AT constandelarevillae omnipolartechnologyinventriculartachycardiaablationactivationandsubstratemappingwithlateactivationisochroneanalysisunderextrastimulusprotocol AT tercedorsanchezl omnipolartechnologyinventriculartachycardiaablationactivationandsubstratemappingwithlateactivationisochroneanalysisunderextrastimulusprotocol AT alvarezlopezm omnipolartechnologyinventriculartachycardiaablationactivationandsubstratemappingwithlateactivationisochroneanalysisunderextrastimulusprotocol |