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Vasculogenic mimicry
Vasculogenic mimicry (VM) refers to the ability of malignant cells to form microvascular channels, having nature of blood vessels but are not endothelium lined. These channels contain blood cells & plasma and provide sufficient nutrient supply to the cancerous cells to meet their metabolic deman...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207198/ https://www.ncbi.nlm.nih.gov/pubmed/37234296 http://dx.doi.org/10.4103/jomfp.jomfp_532_22 |
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author | Pandiar, Deepak Smitha, T Krishnan, Reshma Poothakulath |
author_facet | Pandiar, Deepak Smitha, T Krishnan, Reshma Poothakulath |
author_sort | Pandiar, Deepak |
collection | PubMed |
description | Vasculogenic mimicry (VM) refers to the ability of malignant cells to form microvascular channels, having nature of blood vessels but are not endothelium lined. These channels contain blood cells & plasma and provide sufficient nutrient supply to the cancerous cells to meet their metabolic demands. VM can be seen in various tumors and is associated with their malignant phenotype, high tumor grade, invasion, metastasis and poor clinical outcome. In this paper, we made an attempt to explain the mechanism, visualisation and prognostic significance of vasculogenic mimicry. |
format | Online Article Text |
id | pubmed-10207198 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-102071982023-05-25 Vasculogenic mimicry Pandiar, Deepak Smitha, T Krishnan, Reshma Poothakulath J Oral Maxillofac Pathol Case Report Vasculogenic mimicry (VM) refers to the ability of malignant cells to form microvascular channels, having nature of blood vessels but are not endothelium lined. These channels contain blood cells & plasma and provide sufficient nutrient supply to the cancerous cells to meet their metabolic demands. VM can be seen in various tumors and is associated with their malignant phenotype, high tumor grade, invasion, metastasis and poor clinical outcome. In this paper, we made an attempt to explain the mechanism, visualisation and prognostic significance of vasculogenic mimicry. Medknow Publications & Media Pvt Ltd 2023 2023-03-21 /pmc/articles/PMC10207198/ /pubmed/37234296 http://dx.doi.org/10.4103/jomfp.jomfp_532_22 Text en Copyright: © 2023 Journal of Oral and Maxillofacial Pathology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Pandiar, Deepak Smitha, T Krishnan, Reshma Poothakulath Vasculogenic mimicry |
title | Vasculogenic mimicry |
title_full | Vasculogenic mimicry |
title_fullStr | Vasculogenic mimicry |
title_full_unstemmed | Vasculogenic mimicry |
title_short | Vasculogenic mimicry |
title_sort | vasculogenic mimicry |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207198/ https://www.ncbi.nlm.nih.gov/pubmed/37234296 http://dx.doi.org/10.4103/jomfp.jomfp_532_22 |
work_keys_str_mv | AT pandiardeepak vasculogenicmimicry AT smithat vasculogenicmimicry AT krishnanreshmapoothakulath vasculogenicmimicry |