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A hybrid nanopharmaceutical for specific-amplifying oxidative stress to initiate a cascade of catalytic therapy for pancreatic cancer

BACKGROUND: Oxidative stress (OS) induced by an imbalance of oxidants and antioxidants is an important aspect in anticancer therapy, however, as an adaptive response, excessive glutathione (GSH) in the tumor microenvironment (TME) acts as an antioxidant against high reactive oxygen species (ROS) lev...

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Detalles Bibliográficos
Autores principales: Liu, Fan, Xiang, Qinyanqiu, Luo, Yuanli, Luo, Ying, Luo, Wenpei, Xie, Qirong, Fan, Jingdong, Ran, Haitao, Wang, Zhigang, Sun, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207777/
https://www.ncbi.nlm.nih.gov/pubmed/37221521
http://dx.doi.org/10.1186/s12951-023-01932-0