Enhancing chemical and physical stability of pharmaceuticals using freeze-thaw method: challenges and opportunities for process optimization through quality by design approach

The freeze-thaw (F/T) method is commonly employed during the processing and handling of drug substances to enhance their chemical and physical stability and obtain pharmaceutical applications such as hydrogels, emulsions, and nanosystems (e.g., supramolecular complexes of cyclodextrins and liposomes...

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Detalles Bibliográficos
Autores principales: Bernal-Chávez, Sergio A., Romero-Montero, Alejandra, Hernández-Parra, Héctor, Peña-Corona, Sheila I., Del Prado-Audelo, María L., Alcalá-Alcalá, Sergio, Cortés, Hernán, Kiyekbayeva, Lashyn, Sharifi-Rad, Javad, Leyva-Gómez, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207779/
https://www.ncbi.nlm.nih.gov/pubmed/37221599
http://dx.doi.org/10.1186/s13036-023-00353-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207779/
https://www.ncbi.nlm.nih.gov/pubmed/37221599
http://dx.doi.org/10.1186/s13036-023-00353-9

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